• Publications
  • Influence
High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome.
Hantavirus pulmonary syndrome (HPS) is characterized by the rapid onset of pulmonary edema and a high case-fatality rate. Hantavirus antigens have been demonstrated in pulmonary capillary endothelialExpand
  • 201
  • 18
  • PDF
Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent.
An outbreak of an acute respiratory disease in the southwestern United States has led to the recognition of a new hantaviral illness. This report describes a unique spectrum of antemortem andExpand
  • 236
  • 17
Role of Specific CD8+ T Cells in the Severity of a Fulminant Zoonotic Viral Hemorrhagic Fever, Hantavirus Pulmonary Syndrome1
We report on the role of specific CD8+ T cells in the pathogenesis of a highly lethal human viral disease, hantavirus pulmonary syndrome (HPS). HPS is a zoonotic disease caused by transmission of SinExpand
  • 154
  • 14
Hantavirus Pulmonary Syndrome: A Clinical Description of 17 Patients with a Newly Recognized Disease
Background In May 1993 an outbreak of severe respiratory illness occurred in the southwestern United States. A previously unknown hantavirus was identified as the cause. In Asia hantaviruses areExpand
  • 411
  • 10
Cardiopulmonary manifestations of hantavirus pulmonary syndrome.
OBJECTIVE To describe the clinical characteristics of a group of patients infected with the newly recognized hantavirus in the Southwestern United States. DESIGN Case series. SETTING TertiaryExpand
  • 160
  • 8
Hemolytic-uremic syndrome after shigellosis. Relation to endotoxemia and circulating immune complexes.
To investigate three possible causes of the acute hemolysis in the hemolytic-uremic syndrome, we studied prospectively 207 children and 34 adults with shigellosis in Bangladesh. Nineteen childrenExpand
  • 310
  • 7
Hantavirus cardiopulmonary syndrome.
Hantavirus cardiopulmonary syndrome (HCPS) is caused by infection with multiple types of hantaviruses throughout the Americas. All strains induce a pulmonary capillary leak syndrome with cardiogenicExpand
  • 50
  • 7
Synergistic impact of measles and diarrhoea on nutrition and mortality in Bangladesh.
The association between measles and diarrhea and their effects on weight and mortality were assessed in a prospective household survey in southeast Bangladesh from August 1975 to July 1976. A totalExpand
  • 112
  • 6
Hantavirus pulmonary syndrome: radiographic findings in 16 patients.
PURPOSE To characterize chest radiographic features of Hantavirus pulmonary syndrome. MATERIALS AND METHODS Initial and follow-up chest radiographs from 16 patients with confirmed HantavirusExpand
  • 92
  • 6
Placebo-controlled, double-blind trial of intravenous ribavirin for the treatment of hantavirus cardiopulmonary syndrome in North America.
UNLABELLED BACKGROUND. Ribavirin is active in vitro against hantaviruses, but the findings of an open trial of the use of intravenous ribavirin for the treatment of hantavirus cardiopulmonaryExpand
  • 127
  • 6
  • PDF