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Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment
TLDR
The FAMTX protocol should be the reference treatment in future clinical trials that seek to improve the therapeutic outcome in advanced gastric cancer. Expand
Sequential methotrexate and 5-fluorouracil (FU) vs. FU alone in metastatic colorectal cancer. Results of a randomized multicenter trial. The Association of Medical Oncology (AIO) of the German Cancer
TLDR
It is concluded that this schedule of sequential MTX and FU is no more effective than a dose-intensive treatment with FU alone in metastatic colorectal cancer. Expand
First-line treatment of pancreatic cancer patients with the combination of 5-fluorouracil/folinic acid plus gemcitabine: a multicenter phase II trial by the CONKO-study group
TLDR
The GFF combination appears to be effective and well tolerated in patients with advanced pancreatic cancer and seems to be convenient for patients who are unable to get oral anti-neoplastic medication. Expand
A modified sclerosing needle for the sclerotherapy of upper gastrointestinal bleeding.
TLDR
A modified instrument that permits simultaneous endoscopic irrigation and sclerotherapy of a bleeding site in the gastrointestinal tract under direct visualisation is presented and bleeding was successfully stopped in seven cases of acute upper gastrointestinal hemorrhage. Expand
[A contribution to the rate of side-effects of hepatotropic contrast media. A clinical comparative study of iodoxamate (Endomirabil) and ioglycamid (Bilivistan) (author's transl)].
TLDR
The new substance Iodoxamate (Endomirabil) is a hepatotropic contrast medium and the contrast of the biliary ducts and gall bladder is equivalent compared with Ioglycamid (Bilivistan). Expand
[Fluorouracil as monotherapy or combined with folinic acid in the treatment of metastasizing colorectal carcinoma].
TLDR
The higher rate of response and the significantly prolonged survival time signify an improvement of the therapeutic profile of fluorouracil by addition of folic acid in the palliative therapy of colorectal carcinomas. Expand
[Genetics of Crohn disease: study of the HLA association in 169 patients].
TLDR
The significant association of Crohn's disease and HLA-B12 reported by Smolen et al. could be caused by an increased frequency of HLA -B45 as the authors found in patients. Expand