Antidiabetic Potential of Medicinal Plants and Their Active Components
Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies.
Biological reactive intermediates that mediate dacarbazine cytotoxicity
- J. Pourahmad, M. Amirmostofian, F. Kobarfard, J. Shahraki
- Biology, ChemistryCancer Chemotherapy and Pharmacology
- 28 April 2009
It is suggested that H2O2 could cross the lysosomal membrane, react with lysOSomal Fe2+ to form hydroxyl radical (Haber-Weiss reaction) which is the major cause of lyssomal membrane leakiness, proteases, and other digestive enzymes' release and finally the cell death.
Identification and Determination of Synthetic Pharmaceuticals as Adulterants in Eight Common Herbal Weight Loss Supplements
- M. Khazan, M. Hedayati, F. Kobarfard, S. Askari, F. Azizi
- MedicineIranian Red Crescent Medical Journal
- 1 March 2014
The most undeclared ingredients, which were illegally added include sibutramine, phenolphthalein, bumetanide, and phenytoin in the original super slim, herbaceous essence, super slim green lean, and fat loss, supplements, respectively.
Thymol, thyme, and other plant sources: Health and potential uses
Thymol exhibits antimicrobial, antioxidant, anticarcinogenesis, anti‐inflammatory, and antispasmodic activities, as well as a potential as a growth enhancer and immunomodulator; these bioactivities have been covered.
Plants of the Genus Zingiber as a Source of Bioactive Phytochemicals: From Tradition to Pharmacy
Plants of the genus Zingiber (Family Zingiberaceae) are widely used throughout the world as food and medicinal plants. They represent very popular herbal remedies in various traditional healing…
Developing spray-dried powders containing anthocyanins of black raspberry juice encapsulated based on fenugreek gum
Determination of impurities in illicit methamphetamine samples seized in Iran.
Programmed Cell Death, from a Cancer Perspective: An Overview
A brief outline of PCD types as well as their role in cancer therapeutics is discussed, since irregularities in the cell death process are frequently found in various cancers, key proteins governing cell death type could be used as therapeutic targets for a wide range of cancer.
Evaluation of Emerging Fusarium mycotoxins beauvericin, Enniatins, Fusaproliferin and Moniliformin in Domestic Rice in Iran
- F. Nazari, M. Sulyok, F. Kobarfard, H. Yazdanpanah, R. Krska
- Medicine, BiologyIranian journal of pharmaceutical research
- 1 May 2015
The results showed that 46% of the samples were contaminated with at least one of the emerging mycotoxins and no detectable level of Fusaproliferin and moniliformin was found.
Induction of mitochondrial permeability transition (MPT) pore opening and ROS formation as a mechanism for methamphetamine-induced mitochondrial toxicity
- V. Mashayekhi, M. Eskandari, F. Kobarfard, A. Khajeamiri, M. Hosseini
- BiologyNaunyn-Schmiedeberg's Archives of Pharmacology
The results showed that this agent could induce oxidative stress via rising in mitochondrial reactive oxygen species (ROS) formation, lipid peroxidation, mitochondrial membrane potential collapse, and mitochondrial swelling, and it is suggested that METH could interact with respiratory complexes and METH-induced liver toxicity may be the result of its disruptive effect on mitochondrial respiratory chain.