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Fas ligand in human serum
The Fas ligand (FasL), a member of the tumor necrosis factor family, induces apoptosis in Fas–bearing cells. The membrane–bound human FasL was found to be converted to a soluble form (sFasL) by theExpand
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IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation
Macrophage colony-stimulating factor (M-CSF) regulates the production, survival and function of macrophages through Fms, the receptor tyrosine kinase. Recently, interleukin-34 (IL-34), which sharesExpand
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Design of solids with free-form surfaces
We propose a unified method of generating a wide range of three dimensional objects from polyhedra to solids with free-form surfaces. Modeling systems for polyhedra and systems for free-form surfacesExpand
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Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients
To clarify the cooperative roles of recurrently identified mutations and to establish a more precise risk classification system in acute myeloid leukemia (AML), we comprehensively analyzed mutationsExpand
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Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
The synthetic oleanane triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) and its chemical derivatives induce differentiation and apoptosis of human leukemia cells. The preciseExpand
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Impact of AB0-blood group incompatibility on the outcome of recipients of bone marrow transplants from unrelated donors in the Japan Marrow Donor Program
The findings of this study indicate that major and minor AB0 incompatibility have specific effects on transplant-related mortality and acute graft-versus-host disease in recipients of bone marrowExpand
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Subdivision surface fitting with QEM-based mesh simplification and reconstruction of approximated B-spline surfaces
We present a general method for automatically reconstructing a network of B-spline patches based on the Doo-Sabin subdivision surface. This method consists of two parts, surface fitting and surfaceExpand
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Development of service-oriented products based on the inverse manufacturing concept.
To achieve sustainability, resource consumption and waste generation must be drastically decreased. For societal acceptance, preservation of both quality of life and corporate profits are essential.Expand
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Histiocytic sarcoma of the spleen: case report of asymptomatic onset of thrombocytopenia and complex imaging features
Histiocytic sarcoma of the spleen, in which the malignant cells display morphologic and immunophenotypic features similar to those of mature tissue histiocytes, is a rare but potentially lethalExpand
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An essential role for nuclear factor kappa B in preventing TNF-alpha-induced cell death in prostate cancer cells.
PURPOSE Although tumor necrosis factor-alpha (TNF-alpha) induces a strong cytotoxic effect on cell growth, many authors have reported that various cancer cells are resistant to TNF-alpha and theExpand
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