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National Cooperative Crohn's Disease Study: results of drug treatment.
TLDR
Patients' drug therapy immediately before entry to the study significantly affected subsequent response, and none of the drugs was superior to placebo in prophylaxis against flare-up or recurrence.
Drug-induced pancreatitis: a critical review.
TLDR
The following drugs seem to cause pancreatitis: azathioprine, thiazides, sulfonamides, furosemide, estrogens, and tetracycline; less convincing, but suggestive evidence exists for: 1-asparaginase, iatrogenic hypercalcemia, chlorthalidine, corticosteroids, ethacrynic acid, phenformin, and procainamide.
National Cooperative Crohn's Disease Study: study design and conduct of the study.
TLDR
The study employed a scheme for double-blind evaluation of patient progress which allowed adjustment of prednisone dose according to the degree of illness and ensured continuous monitoring for serious toxicity of any study drug.
Experimental Chronic Portal Vein Bacteremia.∗
TLDR
Preliminary results suggest that: 1) the experimental preparation is satisfactory for studying the chronic infusion of bacteria, toxins, etc. into the portal vein; and 2) chronic portal bacteremia can cause a lesion resembling pericholangitis.
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