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Regional citrate versus systemic heparin for anticoagulation in critically ill patients on continuous venovenous haemofiltration: a prospective randomized multicentre trial.
BACKGROUND Continuous venovenous haemofiltration (CVVH) in the intensive care setting requires anticoagulation to prevent clotting of the extracorporeal circuit. Several protocols avoiding heparinExpand
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Is kidney function altered by the duration of cardiopulmonary bypass?
BACKGROUND Cardiopulmonary bypass (CPB) is considered responsible for kidney damage. By using sensitive markers of kidney damage we assessed whether the length of CPB influences kidney function. Expand
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Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial.
IMPORTANCE Infections due to Staphylococcus aureus are serious complications of cardiothoracic surgery. A novel vaccine candidate (V710) containing the highly conserved S. aureus iron surfaceExpand
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Effects of solvent/detergent‐treated plasma and fresh‐frozen plasma on haemostasis and fibrinolysis in complex coagulopathy following open‐heart surgery
Background and Objectives Solvent/detergent‐treated plasma (SDP) contains markedly lower protein S (PS) and plasmin inhibitor (PI) activity than standard fresh‐frozen plasma (FFP). It has also beenExpand
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Relationship between factor XIII activity, fibrinogen, haemostasis screening tests and postoperative bleeding in cardiopulmonary bypass surgery.
We investigated the relationship between factor XIII, fibrinogen, blood coagulation screening tests and postoperative bleeding in 98 patients undergoing cardiopulmonary bypass (CPB) surgery. AllExpand
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Impact of atrio-biventricular pacing to poor left-ventricular function after CABG.
AIMS The relation between acute postoperative management of epicardial pacing and haemodynamic status in patients with poor left-ventricular function after coronary artery bypass grafting (CABG)Expand
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Volume therapy with a new hydroxyethyl starch solution in cardiac surgical patients before cardiopulmonary bypass.
OBJECTIVE To compare the hemodynamic efficacy of a new hydroxyethyl starch (HES) preparation (130/0.4) with an HES 200/0.5 solution. DESIGN Prospective, randomized, double-blind, phase II study. Expand
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Influence of a new hydroxyethylstarch preparation (HES 130/0.4) on coagulation in cardiac surgical patients.
OBJECTIVE To compare volume therapy with HES 130/0.4, a new hydroxyethylstarch (HES) solution with a gelatin-based fluid replacement strategy. DESIGN Prospective, randomized, safety study. Expand
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Pain management in cardiac surgery patients: comparison between standard therapy and patient-controlled analgesia regimen.
OBJECTIVE To compare standard nurse-based pain therapy with a patient-controlled analgesia (PCA) regimen. DESIGN Prospective, randomized study. SETTING Single-institutional, clinicalExpand
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The influence of allogeneic red blood cell transfusion compared with 100% oxygen ventilation on systemic oxygen transport and skeletal muscle oxygen tension after cardiac surgery.
In this study we investigated the effects of allogeneic red blood cell (RBC) transfusion on tissue oxygenation compared with those of 100% oxygen ventilation by using systemic oxygen transportExpand
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