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Dietary pattern analysis: a new direction in nutritional epidemiology
- F. Hu
- Biology, Medicine
- Current opinion in lipidology
- 1 February 2002
The rationale for studying dietary patterns is described, quantitative methods for analysing dietary patterns and their reproducibility and validity are discussed, and the available evidence regarding the relationship between major Dietary patterns and the risk of cardiovascular disease is discussed. Expand
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
18 new loci associated with body mass index are identified, one of which includes a copy number variant near GPRC5B, and genes in other newly associated loci may provide new insights into human body weight regulation. Expand
2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The…
- M. Jensen, D. Ryan, +16 authors S. Yanovski
- Journal of the American College of Cardiology
- 24 June 2014
This research presents a state-of-the-art online learning system that automates the very labor-intensive and therefore time-heavy and expensive and expensive process of manually cataloging and cataloging students' academic records. Expand
Diabetes in Asia: epidemiology, risk factors, and pathophysiology.
Type 2 diabetes is an increasing epidemic in Asia, characterized by rapid rates of increase over short periods and onset at a relatively young age and low body mass index; prevention and control of diabetes should be a top public health priority in Asian populations. Expand
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity. Expand
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
It is demonstrated that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes. Expand
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
The results illustrate the value of large discovery and follow-up samples for gaining further insights into the inherited basis of T2D, and detect at least six previously unknown loci with robust evidence for association. Expand
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
A meta-analysis of genetic variants on the Metabochip, including 34,840 cases and 114,981 controls, finds a long tail of additional common variant loci explaining much of the variation in susceptibility to type 2 diabetes. Expand
Alternative dietary indices both strongly predict risk of chronic disease.
The findings suggest that closer adherence to the 2005 Dietary Guidelines may lower risk of major chronic disease, however, the AHEI-2010, which included additional dietary information, was more strongly associated with chronic disease risk, particularly CHD and diabetes. Expand
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women.
Independent of exercise levels, sedentary behaviors, especially TV watching, were associated with significantly elevated risk of obesity and type 2 diabetes, whereas even light to moderate activity was associated with substantially lower risk. Expand