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E‐Cadherin Transport from the trans‐Golgi Network in Tubulovesicular Carriers is Selectively Regulated by Golgin‐97
E‐cadherin is a cell–cell adhesion protein that is trafficked and delivered to the basolateral cell surface. Membrane‐bound carriers for the post‐Golgi exocytosis of E‐cadherin have not beenExpand
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A common RET variant is associated with reduced newborn kidney size and function.
Congenital nephron number varies five-fold among normal humans, and individuals at the lower end of this range may have an increased lifetime risk for essential hypertension or renal insufficiency;Expand
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A large family of endosome-localized proteins related to sorting nexin 1.
Sorting nexin 1 (SNX1), a peripheral membrane protein, has previously been shown to regulate the cell-surface expression of the human epidermal growth factor receptor [Kurten, Cadena and Gill (1996)Expand
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Medial Golgi but Not Late Golgi Glycosyltransferases Exist as High Molecular Weight Complexes
To investigate the organization of Golgi glycosyltransferases and their mechanism of localization, we have compared the properties of a number of medial and late acting Golgi enzymes. The medialExpand
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Identification of a novel group of putative Arabidopsis thaliana β-(1,3)-galactosyltransferases
To begin biochemical and molecular studies on the biosynthesis of the type II arabinogalactan chains on arabinogalactan-proteins (AGPs), we adopted a bioinformatic approach to identify andExpand
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A randomized controlled trial of isotonic versus hypotonic maintenance intravenous fluids in hospitalized children
BackgroundIsotonic saline has been proposed as a safer alternative to traditional hypotonic solutions for intravenous (IV) maintenance fluids to prevent hyponatremia. However, the optimal tonicity ofExpand
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The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.
A recently described family of TGN (trans-Golgi network) proteins, all of which contain a GRIP domain targeting sequence, has been proposed to play a role in membrane transport. On the basis of theExpand
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Sorting nexin 5 is localized to a subdomain of the early endosomes and is recruited to the plasma membrane following EGF stimulation
Sorting nexins are a large family of proteins that contain the phosphoinositide-binding Phox homology (PX) domain. A number of sorting nexins are known to bind to PtdIns(3)P, which mediates theirExpand
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A common variant of the PAX2 gene is associated with reduced newborn kidney size.
Congenital nephron number ranges widely in the human population. Suboptimal nephron number may be associated with increased risk for essential hypertension and susceptibility to renal injury, but theExpand
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Steady-state localization of a medial-Golgi glycosyltransferase involves transit through the trans-Golgi network.
The steady-state localization of medial-Golgi enzymes is likely to involve retrograde transport pathways; however, the trafficking of these resident enzymes through the Golgi stack is unclear. ToExpand
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