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Efficacy and safety of benazepril for advanced chronic renal insufficiency.
BACKGROUND Angiotensin-converting-enzyme inhibitors provide renal protection in patients with mild-to-moderate renal insufficiency (serum creatinine level, 3.0 mg per deciliter or less). We assessedExpand
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Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.
IMPORTANCE Uncertainty remains about the efficacy of folic acid therapy for the primary prevention of stroke because of limited and inconsistent data. OBJECTIVE To test the primary hypothesis thatExpand
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Seroprevalence of immunoglobulin M and G antibodies against SARS-CoV-2 in China
Detection of asymptomatic or subclinical novel human coronavirus SARS-CoV-2 infection is critical for understanding the overall prevalence and infection potential of COVID-19. To estimate theExpand
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miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes
Aims/hypothesisAs microRNA-21 (miR-21) plays a pathological role in fibrosis, we hypothesised that it may be a therapeutic target for diabetic nephropathy.MethodsAbundance of miR-21 was examined inExpand
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Sonic hedgehog signaling mediates epithelial-mesenchymal communication and promotes renal fibrosis.
  • H. Ding, Dong Zhou, +5 authors Y. Liu
  • Biology, Medicine
  • Journal of the American Society of Nephrology…
  • 1 May 2012
Sonic hedgehog (Shh) signaling is a developmental signal cascade that plays an essential role in regulating embryogenesis and tissue homeostasis. Here, we investigated the potential role of ShhExpand
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Long-Term Exposure to Air Pollution and Increased Risk of Membranous Nephropathy in China.
The effect of air pollution on the changing pattern of glomerulopathy has not been studied. We estimated the profile of and temporal change in glomerular diseases in an 11-year renal biopsy seriesExpand
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Two-times weekly hemodialysis in China: frequency, associated patient and treatment characteristics and Quality of Life in the China Dialysis Outcomes and Practice Patterns study.
BACKGROUND Renal replacement therapy is rapidly expanding in China, and two-times weekly dialysis is common, but detailed data on practice patterns are currently limited. Using cross-sectional dataExpand
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Advanced oxidation protein products accelerate renal fibrosis in a remnant kidney model.
  • H. Li, F. Hou, +9 authors Di Xie
  • Medicine
  • Journal of the American Society of Nephrology…
  • 1 February 2007
Accumulation of plasma advanced oxidation protein products (AOPP) has been found in patients with chronic kidney disease. However, the biologic consequences of AOPP consumption on progression ofExpand
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Epidemiology and Clinical Correlates of AKI in Chinese Hospitalized Adults.
  • X. Xu, S. Nie, +9 authors F. Hou
  • Medicine
  • Clinical journal of the American Society of…
  • 4 September 2015
BACKGROUND AND OBJECTIVES Comprehensive epidemiologic data on AKI are particularly lacking in Asian countries. This study sought to assess the epidemiology and clinical correlates of AKI amongExpand
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Advanced oxidation protein products activate vascular endothelial cells via a RAGE-mediated signaling pathway.
The accumulation of advanced oxidation protein products (AOPPs) has been linked to vascular lesions in diabetes, chronic renal insufficiency, and atherosclerosis. However, the signaling pathwayExpand
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