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Assessment of health risks with reference to oxidative stress and DNA damage in chromium exposed population.
Genotoxicity and oxidative stress in chromium-exposed tannery workers in North India
- K. Ambreen, F. H. Khan, S. Bhadauria, Sudhir Kumar
- BiologyToxicology and industrial health
- 1 June 2014
The findings of the present study revealed that chronic occupational exposure to trivalent Cr may cause DNA damage and oxidative stress in tannery workers.
Acquired tumor cell radiation resistance at the treatment site is mediated through radiation-orchestrated intercellular communication.
Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes
Analysis of cytogenetic and tumorigenic physiognomies of distinct population of metastatic site- derived aggressive cells from high-risk tumors and the influence of acquired genetic rearrangements on poor patient outcomes suggest that these alterations could switch favorable neuroblastoma to high- risk aggressive disease, promoting poor clinical outcomes.
Association of GSTM1 and GSTT1 gene polymorphisms with COVID‐19 susceptibility and its outcome
The results suggested that COVID‐19 patients with the GSTT1−/− genotype showed higher mortality, and this study investigated the role of GSTM1 and GSTT 1 gene polymorphism with CO VID‐19 susceptibility, as well as its outcome.
Y Chromosome microdeletion and altered sperm quality in human males with high concentration of seminal hexachlorocyclohexane (HCH).
Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling
- V. Pandian, S. Ramraj, F. H. Khan, Tasfia Azim, N. Aravindan
- BiologyStem cell research & therapy
- 20 February 2015
Flexible plasticity and stem-cell related molecular response of aggressive metastatic neuroblastoma cells that typically fit the CSC model are demonstrated and the intrinsic adaptiveness of the successive phenotype switching that clarifies the heterogeneity of HR-NB is identified.
Circadian Rhythm of Serum Cortisol in Female Patients with Fibromyalgia Syndrome
There is an abnormality in circadian secretion of cortisol in female FMS patients, and it could be concluded that there are circadian changes, if any, in serum cortisol levels in women with FMS.
Impact of I/D polymorphism of angiotensin-converting enzyme 1 (ACE1) gene on the severity of COVID-19 patients
Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells
- F. H. Khan, V. Pandian, S. Ramraj, S. Aravindan, T. Herman, N. Aravindan
- BiologyBMC Genomics
- 7 July 2015
For the first time, these results identified a comprehensive list of neuroblastoma metastamiRs, related their deregulation to altered expression of protein targets, and established their association with poor clinical outcomes.