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Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study
Most patients with anti-NMDAR encephalitis respond to immunotherapy; second-line immunotherapy is usually effective when first-line treatments fail, and outcomes continued to improve for up to 18 months after symptom onset. Expand
A clinical approach to diagnosis of autoimmune encephalitis
Through logical differential diagnosis, levels of evidence for autoimmune encephalitis (possible, probable, or definite) are achieved, which can lead to prompt immunotherapy. Expand
Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series
The term limbic encephalitis associated with antibodies against voltage-gated potassium channels should be changed to limbicEncephalitisassociated with LGI1 antibodies, and this disorder should be classed as an autoimmune synaptic encephalopathy. Expand
Recommended diagnostic criteria for paraneoplastic neurological syndromes
- F. Graus, J. Delattre, +9 authors R. Voltz
- Journal of Neurology, Neurosurgery & Psychiatry
- 1 August 2004
An international panel of neurologists interested in PNS recommended new criteria for those in whom no clinical consensus was reached in the past and defined “classical” syndrome and onconeural antibody as “well characterised”. Expand
Anti-Hu-associated paraneoplastic encephalomyelitis: analysis of 200 patients.
The predictors of mortality and PEM evolution found in the study may be important in the design of future therapeutic protocols, and emphasize the importance of early diagnosis and treatment of the underlying tumour. Expand
AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location
To report the clinical and immunological features of a novel autoantigen related to limbic encephalitis (LE) and the effect of patients' antibodies on neuronal cultures.
Anti‐Hu-Associated Paraneoplastic Encephalomyelitis/Sensory Neuronopathy A Clinical Study of 71 Patients
Patients with rapidly developing sensory neuropathy or symptoms of encephalomyelitis should be studied for the presence of the anti-Hu antibody; if the antibody is found, the possibility of small-cell lung cancer should be investigated. Expand
Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen
GABA(B) receptor autoimmune encephalitis is a potentially treatable disorder characterised by seizures and, in some patients, associated with small-cell lung cancer and with other autoantibodies. Expand
Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study
The sensitivity of NMDA receptor antibody testing is higher in CSF than in serum, and antibody titres were higher in patients with poor outcome than in those with good outcome, emphasising the importance of including CSF in antibody studies, and that antibody titre can complement clinical assessments. Expand
Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association.
The demonstration of an increased IS of GAD-ab is important to confirm that the GAD autoimmunity is related to the neurological syndrome particularly when there is a concomitant DM1 that could justify the presence of high G AD-ab levels. Expand