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Diastereomeric quinolinone alkaloids from the marine-derived fungus Penicillium janczewskii.
Cytotoxicity testing on eight tumor cell lines revealed a moderate specificity of 2 on SKOV-3 cells, and two new diastereomeric quinolinones were identified.
Cervimycin A-D: a polyketide glycoside complex from a cave bacterium can defeat vancomycin resistance.
Cervimycins A-D are novel polyketide glycosides with significant activity against multi-drug-resistant staphylococci and vancomycin-resistant enterococci, isolated from an ancient cave.
Biosynthesis of cervimycin C, an aromatic polyketide antibiotic bearing an unusual dimethylmalonyl moiety.
- K. Herold, Zhongli Xu, F. Gollmick, U. Grafe, C. Hertweck
- Chemistry, BiologyOrganic & biomolecular chemistry
- 23 August 2004
The biosynthetic origin of cervimycin was studied by molecular studies and feeding experiments, which reveal that the dimethylmalonate unit is not derived from malonate, but from valine.
Solution structure of a five-adenine bulge loop within a DNA duplex.
- U. Dornberger, A. Hillisch, F. Gollmick, H. Fritzsche, S. Diekmann
- Chemistry, PhysicsBiochemistry
- 8 September 1999
The three-dimensional solution structure of a DNA molecule paired with 5'-d(CGTAGCCGATGC)-3' containing a five-adenine bulge loop (dA(5)-bulge) between two double helical stems was determined by 2D (1)H and (31)P NMR, infrared, and Raman spectroscopy.
Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).
Cervimycin A—D: A Polyketide Glycoside Complex from a Cave Bacterium Can Defeat Vancomycin Resistance.
Interaction of anthracycline antibiotics with biopolymers. VIII. Binding parameters of aclacinomycin A to DNA.
- U. Katenkamp, E. Stutter, I. Petri, F. Gollmick, H. Berg
- Chemistry, BiologyThe Journal of antibiotics
- 1 September 1983
The binding of aclacinomycin A to DNA was investigated spectrophotometrically under equilibrium conditions and the self-association behaviour was identified as dimerization, which was compared with those of adriamycin, daunomycin, and iremycin to draw some conclusions regarding the structural specialities of a clacinomcin A.
352 - Redox processes during photodynamic damage of DNA III. Redox mechanism of photosensitization and radical reaction☆
Hexacyclinol, a new antiproliferative metabolite of Panus rudis HKI 0254.
Hexacyclinol was discovered as a novel, unusual, oligocyclic metabolite in cultures of the fungal strain Panus rudis HKI 0254, isolated from basidiospores of this fungus found on dead betula woods collected near Irkutsk.