N-Heterocyclic Carbenes in Transition Metal Catalysis
- F. Glorius
- Chemistry
- 2007
N-Heterocyclic Carbenes in Catalysis-An Introduction.- N-Heterocyclic Carbenes in Catalysis-An Introduction.- N-Heterocyclic Carbenes as Ligands for High-Oxidation-State Metal Complexes and Oxidation…
An overview of N-heterocyclic carbenes
- M. Hopkinson, C. Richter, M. Schedler, F. Glorius
- ChemistryNature
- 26 June 2014
A concise overview of N-heterocyclic carbenes in modern chemistry is provided, summarizing their general properties and uses and highlighting how these features are being exploited in a selection of pioneering recent studies.
The measure of all rings--N-heterocyclic carbenes.
- T. Dröge, F. Glorius
- ChemistryAngewandte Chemie
- 17 September 2010
Physicochemical data (electronics, sterics, bond strength) of NHCs that are essential for the design, application, and mechanistic understanding of N-Heterocyclic carbenes in catalysis are provided.
C-H bond activation enables the rapid construction and late-stage diversification of functional molecules.
- J. Wencel‐Delord, F. Glorius
- Chemistry, BiologyNature Chemistry
- 1 May 2013
This Perspective highlights the potential of metal-catalysed C-H bond activation reactions, which now extend beyond the field of traditional synthetic organic chemistry, and are more atom- and step-economical than previous methods.
Asymmetric heterogeneous catalysis.
- M. Heitbaum, F. Glorius, I. Escher
- ChemistryAngewandte Chemie
- 17 July 2006
This Review shows that highly ordered metal-organic catalysts that might allow a rational design, synthesis, and the unequivocal structural characterization to give tailor-made catalysts have more to them than facile separation or recycling.
Asymmetric hydrogenation of thiophenes and benzothiophenes.
- S. Urban, Bernhard Beiring, N. Ortega, Daniel Paul, F. Glorius
- ChemistryJournal of the American Chemical Society
- 5 September 2012
An efficient and highly asymmetric ruthenium-N-heterocyclic carbene-catalyzed hydrogenation of substituted thiophenes and benzothiophenes is described, providing a new strategy for the formation of…
A Structure-Based Platform for Predicting Chemical Reactivity
- Frederik Sandfort, Felix Strieth‐Kalthoff, Marius Kühnemund, C. Beecks, F. Glorius
- ChemistryChem
- 21 October 2019
An input based on multiple fingerprint features (MFFs) as a versatile molecular representation was developed that was shown to be applicable over a range of diverse problem sets and predicted molecular properties across a diverse array of molecules accurately.
Application of a chiral metal-organic framework in enantioselective separation.
- Mohan Padmanaban, P. Müller, S. Kaskel
- Chemistry, Materials ScienceChemical Communications
- 31 October 2011
A modular approach for the synthesis of highly ordered porous and chiral auxiliary (Evans auxiliary) decorated metal-organic frameworks is developed, which can provide access to a wide range of porous materials suitable for enantioselective separation and catalysis.
Asymmetric cross-coupling of non-activated secondary alkyl halides.
- F. Glorius
- ChemistryAngewandte Chemie
- 20 October 2008
Low-cost palladium complexes of electron-rich phosphines, in particular P(c-Hex)3 and PtBu2Me, were eventually found to be competent catalysts for the Suzuki–Miyaura coupling and related reactions of primary alkyl halides under mild conditions, and nickel–pybox complexes formed in situ were found toBe the most active and most selective catalysts.
Beyond directing groups: transition-metal-catalyzed C-H activation of simple arenes.
- N. Kuhl, M. Hopkinson, J. Wencel‐Delord, F. Glorius
- ChemistryAngewandte Chemie
- 8 October 2012
In this review, recent advances in the emerging field of non-chelate-assisted C-H activation are discussed, highlighting some of the most intriguing and inspiring examples of induction of reactivity and selectivity.
...
...