Atherosclerotic Renovascular Disease and Progressive Renal Failure
- J. Rimmer, F. Gennari
- MedicineAnnals of Internal Medicine
- 1 May 1993
This review addresses problems and unresolved issues that have developed as a result of new diagnostic and therapeutic technologies, which follow from data on the prevalence and natural history of atherosclerotic renovascular disease, the effects of ACE inhibitors, and the outcome of available therapies.
Current concepts. Serum osmolality. Uses and limitations.
- F. Gennari
- MedicineNew England Journal of Medicine
- 1984
The serum osmolality measurement has a clearly circumscribed use in clinical medicine and provides rapid screening information about the presence of foreign low-molecular-weight solutes in the blood.
Assessing acid-base disorders.
- H. Adrogué, F. Gennari, J. Galla, N. Madias
- MedicineKidney International
- 2 December 2009
A review of three distinct approaches used in assessing acid-base disorders: the physiological approach, the base-excess approach, and the physicochemical approach, to highlight the application of each approach to patient care.
Hyperkalemia: An adaptive response in chronic renal insufficiency.
- F. Gennari, A. Segal
- Medicine, BiologyKidney International
- 1 July 2002
It is proposed that hyperkalemia plays a pivotal role in K+ homeostasis in renal insufficiency by stimulating K+ excretion through an effect that is independent of, and additive to, aldosterone.
Biphasic effects of hemodialysis on platelet reactivity in patients with end-stage renal disease: a potential contributor to cardiovascular risk.
- A. Aggarwal, S. Kabbani, D. Schneider
- Medicine, BiologyAmerican Journal of Kidney Diseases
- 1 August 2002
Although interaction between platelets and the dialysis circuit increases platelet reactivity, continued dialysis decreases platelet reactions, suggesting that increased aggregation after dialysis may be secondary to effects of dialysis on fibrinogen binding, rather than on platelets reactivity.
A definition of proximal and distal tubular compliance. Practical and theoretical implications.
- S. Cortell, F. Gennari, M. Davidman, W. Bossert, W. Schwartz
- MedicineJournal of Clinical Investigation
- 1 September 1973
It is proposed that a knowledge of tubular compliance will be useful in exploring the interrelationships between tubular and peritubular pressures, tubular anatomy, and transtubular ionic permeability.
Disorders of potassium homeostasis. Hypokalemia and hyperkalemia.
- F. Gennari
- MedicineCritical care clinics
- 1 April 2002
Hyperkalemia as a complication of drug therapy.
- J. M. Rimmer, J. F. Horn, F. Gennari
- Medicine, BiologyArchives of Internal Medicine
- 1 May 1987
In more than 80% of the drug-related hyperkalemic episodes, potassium regulation was compromised by underlying disease states, and the most common was renal insufficiency, followed by diabetes mellitus and metabolic acidosis.
Acid‐base assessment of patients receiving hemodialysis. What are our management goals?
- F. Gennari
- Medicine, BiologySeminars in dialysis
- 1 July 2018
The controversies around assessing and treating acid‐base status in HD patients are discussed, a practical approach is recommended, and the new approach provides recommendations for patients both with very low and very high predialysis serum [total CO2] values.
Life-threatening hyperkalemia induced by arginine.
- D. Bushinsky, F. Gennari
- Medicine, BiologyAnnals of Internal Medicine
- 1 November 1978
The profound hyperkalemia that occurred in two patients with severe hepatic disease and moderate renal insufficiency is thought to be the result of an inability to metabolize the administered arginine and excrete the excess extracellular potassium.
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