Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization
- A. Cullinane, A. Straatman-Iwanowska, P. Gissen
- Medicine, BiologyNature Genetics
- 1 April 2010
It is shown that VIPAR forms a functional complex with VPS33B that interacts with RAB11A that has diverse functions in the pathways regulating apical-basolateral polarity in the liver and kidney.
Bone Mineral Density in Children With Untreated and Treated Celiac Disease
Investigating bone mineral density in children with celiac disease at diagnosis and in patients treated for 1 year found a strict gluten-free diet improves bone mineralization, even in 1 year.
Extrahepatic Portal Vein Thrombosis in Children: Etiology and Long-term Follow-up
- F. Gürakan, M. Eren, H. Demir
- MedicineJournal of Clinical Gastroenterology
- 1 April 2004
Prognosis of extrahepatic portal vein thrombosis is good in childhood and propranolol for prophylaxis of variceal bleeding and sclerotherapy might be the preferred modalities.
Cytomegalovirus hepatitis and ganciclovir treatment in immunocompetent children.
- H. Tezer, G. Seçmeer, İ. Saltık-Temizel
- MedicineTurkish Journal of Pediatrics
- 1 May 2008
Although ganciclovir therapy seems to be effective in progressive CMV hepatitis, multicenter randomized studies in a large study group are necessar to determine the efficacy and indications for gancIClovir treatment.
Different features of lung involvement in Niemann-Pick disease and Gaucher disease.
- B. Gülhan, U. Ozcelik, G. Kale
- MedicineRespiratory Medicine
- 1 September 2012
Helicobacter pylori Infection in Turkish Children: Comparison of Diagnostic Tests, Evaluation of Eradication Rate, and Changes in Symptoms after Eradication
- F. Özçay, N. Koçak, F. Gürakan
- MedicineHelicobacter
- 1 June 2004
H. pylori infection is reported to reduce or eliminate abdominal pain and dyspeptic symptoms in children and the rate of reinfection is low after this organism is eradicated.
Fecal calprotectin concentration is increased in children with celiac disease: relation with histopathological findings.
- N. Balamtekin, G. Baysoy, A. Yüce
- MedicineThe Turkish Journal of Gastroenterology
- 2012
Increased fecal calprotectin concentration can be used as a non-invasive marker that might aid in the diagnosis of celiac disease, especially in patients with gastrointestinal presentation and diet adherence in children with Celiac disease.
The Association of Inflammatory Bowel Disease and Mediterranean Fever Gene (MEFV) Mutations in Turkish Children
Although this is a small cohort, disease-causing MEFV mutations and FMF disease rate were increased among patients with IBD, and the increase was prominent among CD patients, whereas in UC the rate was similar to the Turkish healthy control population.
Evaluation of diagnostic parameters of Wilson's disease in childhood.
24-hour urinary copper excretion seems to be the most sensitive test for diagnosis of Wilson's disease, particularly when liver biopsy cannot be performed due to coagulation abnormalities.
Propranolol for primary and secondary prophylaxis of variceal bleeding in children with cirrhosis.
- Ş. Ozsoylu, N. Koçak, H. Demir, A. Yüce, F. Gürakan, H. Ozen
- MedicineTurkish Journal of Pediatrics
- 2000
Propranolol administration is useful for preventing first and recurrent variceal bleeding in Class A cirrhotic patients and in Class B and C cirrhosis patients, it is effective only for preventing the first bleeding episode.
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