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(+/−)‐Naringenin as large conductance Ca2+‐activated K+ (BKCa) channel opener in vascular smooth muscle cells

The aim of this study was to investigate, in vascular smooth muscle cells, the mechanical and electrophysiological effects of (+/−)‐naringenin.
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Quercetin as a novel activator of L‐type Ca2+ channels in rat tail artery smooth muscle cells

Results prove quercetin to be a naturally‐occurring L‐type Ca2+ channel activator and slows both the activation and the deactivation kinetics of the ICa(L).
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Effects of quercetin and rutin on vascular preparations

The mechanical and electrophysiological properties of quercetin and its rutoside, rutin, are investigated in an attempt to clarify how Ca2+ channel activation might be related to the myorelaxing activity.
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The flavonoid scaffold as a template for the design of modulators of the vascular Cav1.2 channels

The proposition that the flavonoid structure confers the ability to modulate Cav1.2 channels is tested and it is shown that it does.
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Rectal temperature and prostaglandin E2 increase in cerebrospinal fluid of conscious rabbits after intracerebroventricular injection of hemoglobin

Findings indicate that, once Hb is released into the subarachnoid space during SAH, it enhances CSF PGE2 content and elicits hyperthermia, thus offering an explanation for the fever that is an aggravating condition in most SAH patients.
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The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels

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Antihypertensive, cardio- and neuro-protective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats

It is suggested that TM can be considered a new functional food that can lower BP in vivo and thus control cardiovascular-associated risk factors such as hypertension.
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The possible role of taurine and GABA as endogenous cryogens in the rabbit: changes in CSF levels in heat-stress.

It is suggested that during heat stress taurine and GABA are released in the extracellular space of brain tissues in higher amounts, as compared to control conditions, to counteract the resulting hyperthermia, thus acting as cryogenic agents.
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Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl.

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Potentiation of mitochondrial Ca2+ sequestration by taurine.

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