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Regulation of chromatin structure by site-specific histone H3 methyltransferases
The organization of chromatin into higher-order structures influences chromosome function and epigenetic gene regulation. Higher-order chromatin has been proposed to be nucleated by the covalentExpand
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Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase
Mobilization of fatty acids from triglyceride stores in adipose tissue requires lipolytic enzymes. Dysfunctional lipolysis affects energy homeostasis and may contribute to the pathogenesis of obesityExpand
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Prediction of potential GPI-modification sites in proprotein sequences.
Glycosylphosphatidylinositol (GPI) lipid anchoring is a common posttranslational modification known mainly from extracellular eukaryotic proteins. Attachment of the GPI moiety to the carboxylExpand
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A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa,
The fungal transamidase complex that executes glycosylphosphatidylinositol (GPI) lipid anchoring of precursor proteins has overlapping but distinct sequence specificity compared with the animalExpand
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Glycosylphosphatidylinositol Lipid Anchoring of Plant Proteins. Sensitive Prediction from Sequence- and Genome-Wide Studies for Arabidopsis and Rice1
Posttranslational glycosylphosphatidylinositol (GPI) lipid anchoring is common not only for animal and fungal but also for plant proteins. The attachment of the GPI moiety to the carboxyl-terminusExpand
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Pds5 cooperates with cohesin in maintaining sister chromatid cohesion
BACKGROUND Sister chromatid cohesion depends on a complex called cohesin, which contains at least four subunits: Smc1, Smc3, Scc1 and Scc3. Cohesion is established during DNA replication, isExpand
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Two Fission Yeast Homologs of Drosophila Mei-S332 Are Required for Chromosome Segregation during Meiosis I and II
BACKGROUND Meiosis produces haploid gametes from diploid progenitor cells. This reduction is achieved by two successive nuclear divisions after one round of DNA replication. Correct chromosomeExpand
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Protein prenyltransferases
SummaryThree different protein prenyltransferases (farnesyltransferase and geranylgeranyltransferases I and II) catalyze the attachment of prenyl lipid anchors 15 or 20 carbons long to the carboxylExpand
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TPR Subunits of the Anaphase-Promoting Complex Mediate Binding to the Activator Protein CDH1
BACKGROUND Chromosome segregation and mitotic exit depend on activation of the anaphase-promoting complex (APC) by the substrate adaptor proteins CDC20 and CDH1. The APC is a ubiquitin ligaseExpand
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Eco1 Is a Novel Acetyltransferase that Can Acetylate Proteins Involved in Cohesion
Cohesion between sister chromatids is established during S phase and maintained through G2 phase until it is resolved in anaphase (for review, see [1-3]). In Saccharomyces cerevisiae, a complexExpand
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