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Primary B-cell gastric lymphoma: a clinicopathological study of 145 patients.
Resection specimens from 145 patients with primary B-cell gastric lymphoma at stage IE (n = 88) and at stage IIE (n = 57) were investigated. Histologically, low-grade malignant B-cell lymphomas… Expand
ATRX immunostaining predicts IDH and H3F3A status in gliomas
- A. Ebrahimi, M. Skardelly, +5 authors J. Schittenhelm
- Acta neuropathologica communications
- 16 June 2016
Gliomas are the most frequent intraaxial CNS neoplasms with a heterogeneous molecular background. Recent studies on diffuse gliomas have shown frequent alterations in the genes involved in chromatin… Expand
Re-surgery and chest wall re-irradiation for recurrent breast cancer - a second curative approach
BackgroundRepeat radiation is a rarely used treatment strategy that must be performed with caution. The efficacy and toxicity of a second curative radiotherapy series was investigated in cases of… Expand
Re‐irradiation of recurrent gliomas: pooled analysis and validation of an established prognostic score—report of the Radiation Oncology Group (ROG) of the German Cancer Consortium (DKTK)
The heterogeneity of high‐grade glioma recurrences remains an ongoing challenge for the interdisciplinary neurooncology team. Response to re‐irradiation (re‐RT) is heterogeneous, and survival data… Expand
Outcome after whole brain radiotherapy alone in intracranial leptomeningeal carcinomatosis from solid tumors
BackgroundThe purpose of the present study was to investigate outcome after whole brain radiotherapy (WBRT) alone as a palliative treatment without concomitant chemotherapy for intracranial… Expand
Cancer-targeted IL-12 controls human rhabdomyosarcoma by senescence induction and myogenic differentiation
- K. Schilbach, Mohammed Alkhaled, +21 authors R. Handgretinger
- Biology, Medicine
- 19 March 2015
Stimulating the immune system to attack cancer is a promising approach, even for the control of advanced cancers. Several cytokines that promote interferon-γ-dominated immune responses show antitumor… Expand
Role of ion channels in ionizing radiation-induced cell death.
- S. Huber, Lena Butz, B. Stegen, L. Klumpp, Dominik Klumpp, F. Eckert
- Chemistry, Medicine
- Biochimica et biophysica acta
- 1 October 2015
Neoadjuvant, adjuvant or definitive fractionated radiation therapy are implemented in first line anti-cancer treatment regimens of many tumor entities. Ionizing radiation kills the tumor cells mainly… Expand
Cerebral metastases in extrapulmonary cell carcinoma
Background and purposeExtrapulmonary small cell carcinoma (EPSCC) is a rare disease. Standard treatment is performed in analogy to small cell lung cancer; however, due to the differences in rates of… Expand
Limited disease of extra-pulmonary small cell carcinoma
PurposeAs extra-pulmonary small cell carcinoma (EPSCC) is a rare entity of tumors, the available treatment recommendations are mainly based on retrospective analyses and deduction from treatment of… Expand
The Prognostic Impact of Ventricular Opening in Glioblastoma Surgery: A Retrospective Single Center Analysis.
OBJECTIVE Ventricular opening during glioblastoma (GBM) resection is controversial. Sufficient evidence regarding its prognostic role is missing. We investigated the impact of ventricular opening on… Expand