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A simple spectrophotometric method for metallothionein evaluation in marine organisms: an application to Mediterranean and Antarctic molluscs
Abstract A spectrophotometric method to evaluate the concentration of metallothioneins in the tissues of marine organisms has been developed. Metallothionein concentration was evaluated utilizing aExpand
Quantitative PCR analysis of two molluscan metallothionein genes unveils differential expression and regulation.
Data indicate that the MT isogenes are differentially regulated by heavy metals, while hydroxyl radicals may have a role in MT20 gene activation. Expand
A “Weight-of-Evidence” Approach for the Integration of Environmental “Triad” Data to Assess Ecological Risk and Biological Vulnerability
The EDSS has been applied in the integration of a battery of Triad data obtained during the European Union-funded Life Intervention in the Fraschetta Area project, which has been carried out in order to estimate the potential risk from soils of a highly anthropized area mainly impacted by deposition of atmospheric pollutants. Expand
Metabolic profiling of Mytilus galloprovincialis and its potential applications for pollution assessment
The study demonstrates the potential of NMR-based metabolomics to provide a rapid and cost-effective screening tool for monitoring the aquatic environment with a significantly different response to those given the mixture. Expand
Biochemical characterization and quantitative gene expression analysis of the multi-stress inducible metallothionein from Tetrahymena thermophila.
A cadmium-binding protein with biochemical features of a metallothionein has been isolated and purified to homogeneity from the ciliate Tetrahymena thermophila and a general role of this protein in stress response is indicated. Expand
Common strategies and technologies for the ecosafety assessment and design of nanomaterials entering the marine environment.
This Nano Focus examines key issues related to the state-of-the-art models and analytical tools being developed to understand ecological risks and to design safeguards for marine organisms. Expand
Gene Expression Rhythms in the Mussel Mytilus galloprovincialis (Lam.) across an Annual Cycle
Seasonal environmental changes may affect the physiology of Mytilus galloprovincialis, an intertidal filter-feeder bivalve occurring commonly in Mediterranean and Atlantic coastal areas, and Physiological response to thermal variation, food availability, and reproductive status across months may contribute to variation in relative mRNA abundance. Expand
Integration of biochemical, histochemical and toxicogenomic indices for the assessment of health status of mussels from the Tamar Estuary, U.K.
It is concluded that the MES is a valuable tool that permits integration and interpretation of complex sets of biomarkers data by identifying the biological meaning of biomarker changes. Expand
Occurrence of Cu-ATPase in Dictyostelium: possible role in resistance to copper.
Although no evidence of Cu-inducible metallothionein was found, Cu-dependent ATPase activity was cytochemically detected on pelletted, resin-embedded amoebae and revealed the occurrence of a Cu-Inducible, putative homologue of human Menkes (MNK) Cu-P-type ATPase. Expand
Interactions of a pesticide/heavy metal mixture in marine bivalves: a transcriptomic assessment
While toxicokinetic modeling did not explain mixture interactions, gene expression profiling and further Gene Ontology-based functional genomics analysis provided clues that the decrement of toxicity may arise from the development of specific toxicodynamics. Expand