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Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage.
TLDR
There is still controversy over whether analytical techniques currently in use are able to identify the level of damage to spermatozoa and large-scale studies should be conducted in different clinical settings to determine the effects of sperm DNA damage on the outcome of ART.
Lipids of the sperm plasma membrane: from polyunsaturated fatty acids considered as markers of sperm function to possible scavenger therapy.
TLDR
A specific composition of phospholipids and a significant concentration of polyunsaturated fatty acids (PUFA) have been shown to be present in sperm membranes and Seminal plasma has a highly specialized scavenger system that defends the sperm membrane against lipoperoxidation.
Study of apoptotic DNA fragmentation in human spermatozoa.
TLDR
The results suggest that apoptosis could be the final result of various pathologies and of a deregulation of spermatogenesis control systems.
Fatty acid composition of spermatozoa and immature germ cells.
TLDR
This study demonstrates that the human germ cell line can elongate and desaturate essential fatty acids and that the percentage of long-chain PUFA is correlated with the normal morphology of sperm cells.
Semen analysis in HIV seropositive men and in subjects at high risk for HIV infection.
TLDR
A comparative study of sperm parameters in human immunodeficiency virus (HIV) seropositive and high risk subjects was performed in order to identify any possible alterations in the semen which specifically result from HIV infection and to study the p24 antigen as an early diagnostic marker of infection in high risk Subjects.
Human sperm cryopreservation and reactive oxygen species (ROS) production.
TLDR
It seems, therefore, that cryoprocedure can indeed provoke or increase ROS production in some semen samples, and in ROS producing subjects, the post-show recovery of sperm motility and vitality was significantly lower compared to ROS-free subjects.
Testicular cancer and Hodgkin's disease: evaluation of semen quality.
TLDR
Better semen quality was observed in patients with HD than in those with TC, and seems better than previous results reported in the literature.
Improved Human Sperm Recovery Using Superoxide Dismutase and Catalase Supplementation in Semen Cryopreservation Procedure
TLDR
The results suggest that, in some selected cases, SOD and catalase supplementation can contribute greatly to the prevention of sperm membrane lipid peroxidation by ROS and thus allow good sperm parameter recovery after freezing–thawing procedures.
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