• Publications
  • Influence
Comparison of inflammatory changes in established type II collagen- and adjuvant-induced arthritis using outbred Wistar rats.
Type II collagen- and adjuvant-induced arthritis in outbred Wistar rats were compared using parameters that measured the inflammatory response, cellular and humoral immunity, blood protein changes,Expand
Reaction to Injectable Collagen: Results in Animal Models and Clinical Use
Since its commercial release, Zyderm collagen implant has been used to treat more than 200,000 subjects in the United States for soft-tissue contour defects and more than 250,000 patientsExpand
Clinical use of injectable bovine collagen: a decade of experience.
Bovine collagen has long been recognized as a safe, highly biocompatible material. In 1981 and 1985, two injectable fibrillar suspensions of purified bovine dermal collagen, Zyderm and ZyplastExpand
Characterization of the release of human monocyte regulators of fibroblast proliferation.
We have examined the mechanism of release of monocyte-derived mediators that stimulate fibroblast proliferation in vitro. Adherence of human monocytes promotes the rapid release of these factors andExpand
Serological analysis of patients treated with a new surgical hemostat containing bovine proteins and autologous plasma.
A randomized, controlled clinical study of the management of diffuse bleeding with CoStasis surgical hemostat, a new hemostat containing bovine thrombin and collagen with the patient's own plasma,Expand
A comparative study of the biologic and immunologic response to medical devices derived from dermal collagen.
We examined collagen materials for soft tissue augmentation [Zyderm Collagen Implant (ZCI), glutaraldehyde cross-linked (GAX) collagen, and Koken Atelocollagen (Atelocollagen)]; hemostatic collagensExpand
Immune responses to allogeneic and xenogeneic implants of collagen and collagen derivatives.
Whereas xenogeneic collagen has provided a safe and effective biomaterial for numerous medical applications, there are few instances in which data permit the correlation of the immunologic profile ofExpand
Antibodies to collagen in scleroderma.
Using the enzyme-linked immunosorbent assay (ELISA), we detected antibodies to interstitial (type I) and basement membrane (type IV) collagens in the sera of patients with scleroderma (systemicExpand
Evaluation of Artecoll Polymethylmethacrylate Implant for Soft‐Tissue Augmentation: Biocompatibility and Chemical Characterization
&NA; Artecoll polymethylmethacrylate implant (Artecoll) is a combination of polymethylmethacrylate beads suspended in 3.5% atelocollagen and has been designed for use in soft‐tissue augmentationExpand
Three siblings with scleroderma (systemic sclerosis) and two with Raynaud's phenomenon from a single kindred.
A kindred is reported which contains 3 siblings with scleroderma, 2 siblings with Raynaud's phenomenon, and 2 first-degree relatives with histories suggestive of connective tissue syndromes. StudiesExpand