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Biosimilar Infliximab in Inflammatory Bowel Disease: Outcomes of a Managed Switching Programme
TLDR
A managed switching programme from originator infliximab to biosimilar CT-P13 in IBD, using a gain-share agreement, delivers significant cost savings and investment in clinical services while maintaining similar patient-reported outcomes, biochemical response, drug persistence, and adverse event profile. Expand
Nationwide improvement in outcomes of emergency admission for ulcerative colitis in England, 2005‐2013
The UK IBD Audit Programme reported improved inpatient care processes for ulcerative colitis (UC) between 2005 and 2013. There are no independent data describing national or institutional trends inExpand
OC-008 Virtual inflammatory bowel disease clinics in the real world
TLDR
The IBD Virtual Clinic is an effective alternative model for following up patients with stable IBD that meets the IBD Standards for follow-up of patients and is applied to coeliac disease and Barrett's oesophagus. Expand
EFFICACY OF HIGH AND LOW DOSE ORAL VITAMIN D REPLACEMENT THERAPY IN INFLAMMATORY BOWEL DISEASE (IBD): SINGLE CENTRE COHORT
TLDR
Oral vitamin D replacement is an effective treatment for vitamin D deficiency in IBD patients and appears to be dose responsive, in both Crohn's disease and ulcerative colitis patients. Expand
PTH-090 Monitoring unplanned care and surgical events for crohn’s disease patients treated with biologics in england: linkage of routine administrative data and uk ibd registry
Introduction The UK IBD Registry (UK-IBD-R) is developing analyses of Hospital Episode Statistics (HES) with linkage to locally-recorded registry data to generate aggregated reports and indicators toExpand
PTH-126 Audit of biological therapy for inflammatory bowel disease: results from the UK IBD registry
TLDR
Results highlight an ongoing need for most centres to improve biologics monitoring through better-organised and documented review visits with objective recording of standardised outcomes. Expand
OTU-26 Data driven service evaluation of an IBD helpline
TLDR
A data driven service evaluation of the use of an Inflammatory Bowel Disease telephone helpline service at a single UK IBD centre (UHS) demonstrates how such evaluation can highlight service improvement needs to maximise efficiency and improve patient care. Expand
Gastroenterology Service OTU-028 BENCHMARKING OF ACTIVITY , PROCESS AND OUTCOME OF EMERGENCY ADMISSION FOR ULCERATIVE COLITIS ACROSS ENGLISH HOSPITALS 1
Introduction The UK IBD Registry aims to make information work better for patients, clinical teams and the NHS. As part of the benchmarking reports provided to participating Trusts, we have developedExpand
AODTH-005 Transcriptomic profiling of intestinal macrophages isolated from patients reveals a profound gene expression reprogramming underlying ibd pathogenesis
TLDR
The first study to describe the transcriptome of intestinal macrophages from active lesions of patients with IBD by high throughput RNAseq is described, showing that the transcriptomes of these macrophage is profoundly different from those taken from healthy subjects. Expand
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