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Monocular deprivation decreases the expression of messenger RNA for brain-derived neurotrophic factor in the rat visual cortex
We found that deprivation of pattern vision in one eye, that leaves luminance detection performance unaffected, is sufficient to reduce brain-derived neurotrophic factor (but not trkB) messenger RNAExpand
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Emx2 Promotes Symmetric Cell Divisions and a Multipotential Fate in Precursors from the Cerebral Cortex
Distinct sets of precursor cells generate the mammalian cerebral cortex. During neurogenesis most precursors are specified to generate a single cell type and only few are multipotent. TheExpand
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Cell cycle and cell fate interactions in neural development
Mechanisms coupling cell cycle and cell fate operate at different steps during neural development. Intrinsic factors control the cell proliferation of distinct brain regions and changes of cell fateExpand
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MicroRNAs couple cell fate and developmental timing in retina
Cell identity is acquired in different brain structures according to a stereotyped timing schedule, by accommodating the proliferation of multipotent progenitor cells and the generation of distinctExpand
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Xrx1 controls proliferation and neurogenesis in Xenopus anterior neural plate
In Xenopus neuroectoderm, posterior cells start differentiating at the end of gastrulation, while anterior cells display an extended proliferative period and undergo neurogenesis only at tailbudExpand
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Dystroglycan is required for proper retinal layering.
Dystroglycan (DG) is a transmembrane receptor linking the extracellular matrix to the internal cytoskeleton. Its structural function has been mainly characterized in muscle fibers, but DG playsExpand
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Xrx1 controls proliferation and multipotency of retinal progenitors
We investigated the function of Xrx1 during Xenopus retinogenesis. Xrx1 overexpression lengthens mitotic activity and ectopically activates the expression of markers of undifferentiated progenitorsExpand
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Timing the Generation of Distinct Retinal Cells by Homeobox Proteins
The reason why different types of vertebrate nerve cells are generated in a particular sequence is still poorly understood. In the vertebrate retina, homeobox genes play a crucial role inExpand
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MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development
tbx5, a member of the T-box gene family, encodes one of the key transcription factors mediating vertebrate heart development. Tbx5 function in heart development appears to be exquisitely sensitive toExpand
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Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis.
Maturation of miRNAs by dicer is required in vertebrates for normal neural development. Here we report that dicer inactivation in Xenopus affects cell cycle progression, survival and timing of theExpand
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