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Antibacterial activity of Brazilian propolis and fractions against oral anaerobic bacteria.
TLDR
Propolis collected from a cerrado area in Minas Gerais State, Brazil, was subjected to chromatography on silica gel column and to partition between immiscible solvents and yielded fractions which were active against bacteria. Expand
Anti-biofilm activity of Marula - a study with the standardized bark extract.
TLDR
The standardized extract significantly disrupted the quorum sensing mediated production of biofilm formation and also inhibited swarming ability of the cells, illustrating the anti-biofilm property Sclerocarya birrea. Expand
Hancornia speciosa Gomes induces hypotensive effect through inhibition of ACE and increase on NO.
TLDR
The present work demonstrated that Hanc California speciosa has a potent hypotensive effect in normotensive mice and support the use of Hancornia speciose by traditional medicine as antihypertensive. Expand
Antiedematogenic activity and phytochemical composition of preparations from Echinodorus grandiflorus leaves.
TLDR
The biological activity correlated positively with the contents of flavonoids and diterpenes, but negatively with HCTA concentrations, demonstrating the participation of the two classes of compounds in the antiedematogenic activity of E. grandiflorus. Expand
Development and validation of a RP-HPLC method for quantification of isoflavone aglycones in hydrolyzed soy dry extracts.
TLDR
The development and validation of an isocratic reversed-phase HPLC method for the analysis of isoflavone aglycones, released after acid hydrolysis of soy dry extracts, used as pharmaceutical raw material are described. Expand
Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium
TLDR
Data support the potential chemopreventive activity of constituents from H. coronarium rhizomes in terms of inhibition of NF-κB, COX-1 and -2, the induction of antioxidant response element (ARE), and the inhibition of cell proliferation. Expand
Endothelium-dependent vasodilation induced by Hancornia speciosa in rat superior mesenteric artery.
TLDR
It is concluded that HSE induces an endothelium-dependent vasodilation in rat mesenteric artery, by a mechanism dependent on NO, on the activation of potassium channels and endothelia-derived hyperpolarizing factor release. Expand
Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids.
TLDR
This review discusses these two approaches, presents briefly the screening methodologies for evaluation of antimalarial activity and focuses the activity of alkaloids belonging to different structural classes as well as its importance as new antimalaria drugs or leads and chemical markers for phytomedicines. Expand
Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts.
TLDR
A new method for the in vitro screening of plant extracts with potential angiotensin-converting enzyme (ACE) inhibitory activity is proposed, which involves only inexpensive reagents and apparatus and shows good correlation with a HPLC assay already established for the screening of ACE inhibitors. Expand
Evaluation of Brazilian plants on cancer chemoprevention targets in vitro
TLDR
Several extracts / fractions were active in more than one assay and those from H. speciosa, M. hirsuta and J. caroba mediated strong responses with NF‐κB, COX‐1 and ARE, respectively. Expand
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