F. Burkhalter

Publications39
h-index13
Citations709
Highly Influential Citations32
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FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair
TLDR
It is shown that cells from individuals with FAN1 mutations have sensitivity to the ICL-inducing agent mitomycin C but do not exhibit chromosome breakage or cell cycle arrest after diepoxybutane treatment, unlike cells from Individuals with Fanconi anemia.
Combined array comparative genomic hybridization and tissue microarray analysis suggest PAK1 at 11q13.5-q14 as a critical oncogene target in ovarian carcinoma.
Clinical consequences of non adherence to immunosuppressive medication in kidney transplant patients
TLDR
A negative result suggests that high adherence may protect patients against detrimental clinical outcomes, and/or that immunosuppressive regimens containing newer drugs allow wider non adherence margins than those based on previous generation medications such as cyclosporine, azathioprine and corticosteroids.
Detection of Clinical and Subclinical Tubulo‐Interstitial Inflammation by the Urinary CXCL10 Chemokine in a Real‐Life Setting
TLDR
In real life, urinary CXCL10 had clinically useful diagnostic properties making it a candidate biomarker to guide allograft biopsies, and it correlated well with the extent of tubulo‐interstitial inflammation.
A Comparison of Two Types of Rabbit Antithymocyte Globulin Induction Therapy in Immunological High-Risk Kidney Recipients: A Prospective Randomized Control Study
TLDR
No significant differences were found between the compared study drugs for induction treatment in immunological high-risk patients regarding safety and efficacy during follow-up with good allograft function at 2 years after transplantation.
[The risk of living kidney donation].
  • F. Burkhalter
  • Medicine
    Therapeutische Umschau. Revue therapeutique
  • 2011
TLDR
The following manuscript summarizes the medical and psychological evaluations of live kidney donors and delivers insight in the risks and the possible long-term effects of living kidney donation.
Early complications after living donor nephrectomy: analysis of the Swiss Organ Living Donor Health Registry.
TLDR
A low rate of major and minor complications, independent of surgical technique, after living donor nephrectomy was found, and there was no elevated complication rate in obese donors.
Acute Rejection Phenotypes in the Current Era of Immunosuppression: A Single-Center Analysis
TLDR
Suspicious for rejection phenotypes are very common in the current era and outnumber the frequency of ‘definitive rejection’ within the first year posttransplant.
Prevalence and risk factors for chronic kidney disease in a rural region of Haiti.
TLDR
A high prevalence of CKD and traditional risk factors, and their association with CKD in Haiti is shown, and these findings have now to be confirmed in other regions in longitudinal analyses as a basic step to build up screening and prevention programmes for CKD.
Pseudomonas exit-site infection: treatment outcomes with topical gentamicin in addition to systemic antibiotics
TLDR
Eradication of Pseudomonas ESI remains difficult even with the addition of topical gentamicin to the exit site, and there should be a low threshold for catheter replacement.
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