Exudative, cellular and humoral reactions to platelet-activating factor (PAF-acether) in the pleural cavity of rats.
Pharmacological modulation of PAF-acether-induced pleurisy in rats.
Pharmacological studies on zymosan inflammation in rats and mice. 2: Zymosan-induced pleurisy in rats.
Pharmacological studies on zymosan inflammation in rats and mice. 1: Zymosan-induced paw oedema in rats and mice.
Antiallergic and anti-inflammatory action of tioxamast in rats. II. Anti-inflammatory action in vivo.
- J. Tarayre, M. Aliaga, J. Tisne-Versailles
- Medicine, BiologyInternational Archives of Allergy and Applied…
Tioxamast has an anti-inflammatory effect in vivo in various nonimmunological models in rats and is a potentially useful drug in the treatment of allergies in humans.
Biochemical Changes and Morphological Alterations of Liver and Kidney in Hamsters after Administration of the HMG‐Coenzyme A Reductase Inhibitor, Simvastatin: Prevention and Reversibility by…
- P. Oms, N. Assie, F. Bruniquel, A. Degryse, G. V. Haverbeke, A. Delhon
- Biology, Medicine
- 1 December 1995
It is suggested that the dramatic effect of simvastatin could result from depletion of a non-sterol metabolite of mevalonate in spite of a lack of protective effects of farnesol and geranylgeraniol in the following study.
Anti-Atherosclerotic Properties of the Acyl-coenzyme A:Cholesterol Acyltransferase Inhibitor F 12511 in Casein-Fed New Zealand Rabbits
- Y. Rival, D. Junquéro, A. Delhon
- Medicine, BiologyJournal of Cardiovascular Pharmacology
- 1 February 2002
The data suggest that the combination of endogenous hypercholesterolemia with endothelial injury in the rabbit may offer a useful model to study atherosclerosis; lipid lowering by F 12511 reduces the incidence of vascular lesions and macrophage infiltration and may reinforce the fibrous skeleton of the atheroma.
F 12511, a novel ACAT inhibitor, and atorvastatin regulate endogenous hypercholesterolemia in a synergistic manner in New Zealand rabbits fed a casein-enriched diet.
Effects of the new hypolipidemic agent F 2833 on plasma lipoprotein levels in normal and hyperlipidemic hamsters.
- P. Oms, F. Bruniquel, L. Puech, A. Delhon
- BiologyMethods and Findings in Experimental and Clinical…
- 1 September 1992
F 2833 thus decreased plasma lipids in hamsters that were fed on hyperlipidemic diet to normal values observed in animals fed a standard diet, confirming and extending findings previously obtained in other animal species.
Biochemical changes and morphological alterations of liver and kidney in hamsters after administration of the HMG-coenzyme A reductase inhibitor, simvastatin: prevention and reversibility by…