EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update
- J. Smolen, R. Landewé, D. M. van der Heijde
- MedicineAnnals of the Rheumatic Diseases
- 25 October 2013
The 2010 European League against Rheumatism recommendations for the management of rheumatoid arthritis (RA) with synthetic and biological disease-modifying antirheumatic drugs (sDMARDs and b DMARDs, respectively) have been updated and are intended to improve outcome in patients with RA.
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs
- J. Smolen, R. Landewé, D. M. van der Heijde
- MedicineAnnals of the Rheumatic Diseases
- 5 May 2010
Recommendations are intended to inform rheumatologists, patients and other stakeholders about a European consensus on the management of RA with DMARDs and GCs as well as strategies to reach optimal outcomes of RA based on evidence and expert opinion.
Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis.
- R. Maini, F. Breedveld, M. Feldmann
- MedicineArthritis & Rheumatism
- 1 September 1998
Multiple infusions of cA2 were effective and well tolerated, with the best results occurring at 3 and 10 mg/kg either alone or in combination with MTX in approximately 60% of patients with active RA despite therapy with low-dose MTX.
The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide.
- G. A. Schellekens, H. Visser, W. V. van Venrooij
- Medicine, BiologyArthritis & Rheumatism
- 2000
The anti-CCP ELISA might be very useful for diagnostic and therapeutic strategies in RA of recent onset and appears to be highly specific for RA, using prevalent RA and non-RA sera.
Treating rheumatoid arthritis to target: recommendations of an international task force
- J. Smolen, D. Aletaha, D. M. van der Heijde
- MedicineAnnals of the Rheumatic Diseases
- 9 March 2010
The 10 recommendations are supposed to inform patients, rheumatologists and other stakeholders about strategies to reach optimal outcomes of RA based on evidence and expert opinion.
The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with…
- F. Breedveld, M. Weisman, G. Spencer-Green
- Medicine, PsychologyArthritis & Rheumatism
- 2006
Combination therapy with adalimumab plus MTX was significantly superior to either MTX alone or ad alimumab alone in improving signs and symptoms of disease, inhibiting radiographic progression, and effecting clinical remission in patients with early, aggressive rheumatoid arthritis.
Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force
- J. Smolen, F. Breedveld, D. M. van der Heijde
- MedicineAnnals of the Rheumatic Diseases
- 12 May 2015
The 4 overarching principles and 10 recommendations are based on stronger evidence than before and are supposed to inform patients, rheumatologists and other stakeholders about strategies to reach optimal outcomes of RA.
How to diagnose rheumatoid arthritis early: a prediction model for persistent (erosive) arthritis.
- H. Visser, S. le Cessie, K. Vos, F. Breedveld, J. Hazes
- MedicineArthritis & Rheumatism
- 1 February 2002
A clinical prediction model was developed with an excellent ability to discriminate, at the first visit, between 3 forms of arthritis outcome, and validation in other early arthritis clinics is necessary.
Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial.
- Y. Goekoop-Ruiterman, J. D. de Vries-Bouwstra, B. Dijkmans
- MedicineArthritis & Rheumatism
- 1 November 2005
In patients with early RA, initial combination therapy including either prednisone or infliximab resulted in earlier functional improvement and less radiographic damage after 1 year than did sequential monotherapy or step-up combination therapy.
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