• Publications
  • Influence
Practice parameter for the diagnosis and management of primary immunodeficiency.
The American Academy of Allergy, Asthma & Immunology (AAAAI) and the American College of Allergy, Asthma & Immunology (ACAAI) have jointly accepted responsibility for establishing the "PracticeExpand
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Adaptive immunity.
The innate immune system provides critical mechanisms for the rapid sensing and elimination of pathogens. Adaptive immunity has evolved to provide a broader and more finely tuned repertoire ofExpand
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Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology.
Human immunoglobulin prepared for intravenous administration (IGIV) has a number of important uses in the treatment of disease. Some of these are in diseases for which acceptable treatmentExpand
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Population Prevalence of Diagnosed Primary Immunodeficiency Diseases in the United States
Boyle JM, Buckley RH. J Clin Immunol. 2007;27(5):497–502 PURPOSE OF THE STUDY. To measure the prevalence of primary immunodeficiency diseases (PIDs) in the United States. STUDY POPULATION. A randomExpand
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Update on the use of immunoglobulin in human disease: A review of evidence
&NA; Human immunoglobulin preparations for intravenous or subcutaneous administration are the cornerstone of treatment in patients with primary immunodeficiency diseases affecting the humoral immuneExpand
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Presenting Phenotype in 100 Children With the 22q11 Deletion Syndrome
Purpose of the Study. To describe the clinical presentations of individuals having deletion of the 22q11 region. Study Population. The first 100 individuals <20 years old presenting to the QueenExpand
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Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome.
BACKGROUND Mutations in signal transducer and activator of transcription (STAT) 1 cause a broad spectrum of disease, ranging from severe viral and bacterial infections (amorphic alleles) to mildExpand
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The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation.
BACKGROUND An increasing number of rare genetic defects are associated with immunodeficiency and impaired ability to activate gene transcription through nuclear factor (NF) kappaB. HypomorphicExpand
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Development of Population-Based Newborn Screening for Severe Combined Immunodeficiency
Purpose of the Study. To evaluate analysis of T-cell development as a potential population-screening method for severe combined immunodeficiency (SCID). Study Population. Twenty-three infants withExpand
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Pharmacokinetics of immunoglobulin administered via intravenous or subcutaneous routes.
  • F. Bonilla
  • Medicine
  • Immunology and allergy clinics of North America
  • 1 November 2008
This article reviews pharmacokinetic studies of IgG administration by intravenous and subcutaneous routes. Intravenous immunoglobulin pharmacokinetics have been studied during replacement therapy forExpand
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