• Publications
  • Influence
The HCL-32: towards a self-assessment tool for hypomanic symptoms in outpatients.
TLDR
The performance of the scale in distinguishing individuals with BP from those with major depressive disorder and the HCL-32 distinguished between BP and MDD with a sensitivity of 80% and a specificity of 51%. Expand
Toward a re-definition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar-II, minor bipolar disorders and hypomania.
TLDR
The diagnostic criteria of hypomania need revision and a broader concept of soft bipolarity is proposed, of which nearly 11% constitutes the spectrum of bipolar disorders proper, and another 13% probably represent the softest expression of bipolarity intermediate between bipolar disorder and normality. Expand
Agitated "unipolar" depression re-conceptualized as a depressive mixed state: implications for the antidepressant-suicide controversy.
TLDR
Agitated depression emerges as a distinct affective syndrome with weight loss, pressure of speech, racing thoughts and suicidal ideation, which overall accord with classical German concepts of agitated depression as a mixed state. Expand
Bipolar disorder—focus on bipolar II disorder and mixed depression
TLDR
Prevalence of mixed depression, a combination of depression and manic or hypomanic symptoms, is high in patients with bipolar disorders, and controlled studies are needed to investigate treatment of mixed depressed; antidepressants can worsen manic and hypomania symptoms, and mood stabilising agents might be necessary. Expand
A cross-sectional study of the prevalence of cognitive and physical symptoms during long-term antidepressant treatment.
TLDR
Physical and cognitive symptoms are frequently reported by MDD patients who have responded to antidepressants and are treated in the long term with these agents, and it is likely that these symptoms are both side effects of the antidepressants as well as residual symptoms of MDD. Expand
Prevalence of bipolar II disorder in outpatient depression: a 203-case study in private practice.
  • F. Benazzi
  • Psychology, Medicine
  • Journal of affective disorders
  • 1 April 1997
TLDR
Of 203 consecutive major depressed outpatients in a private setting, 45% had bipolar II disorder, 51% had unipolar depression, and 4% hadipolar I disorder, suggesting that the depressive phase of bipolar II Disorder differs only in one, but important, dimension (atypical features) from un bipolar depression in aPrivate setting. Expand
The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention.
TLDR
The rates of mixed depression among bipolar and non-bipolar depressive suicide attEMPters were much higher than previously reported among nonsuicidal bipolar II and unipolar depressive outpatients, suggesting that suicide attempters come mainly from mixed depressives with predominantly bipolar II base. Expand
Symptoms of depression as possible markers of bipolar II disorder
  • F. Benazzi
  • Medicine, Psychology
  • Progress in Neuro-Psychopharmacology and…
  • 1 May 2006
TLDR
Hypersomnia, racing/crowded thoughts, irritability, and psychomotor agitation may be useful, cross-sectional markers of BP-II, and should lead the clinician to careful probing for history of hypomania, which should reduce the BP- II misdiagnosed as MDD. Expand
Refining the evaluation of bipolar II: beyond the strict SCID-CV guidelines for hypomania.
TLDR
Systematic probing for all past Hypomanic symptoms and behaviors, independently of the answer to the screening question on mood, can elicit hypomanic features that would otherwise be discarded by strict adherence to the SCID-CV. Expand
Delineating bipolar II mixed states in the Ravenna-San Diego collaborative study: the relative prevalence and diagnostic significance of hypomanic features during major depressive episodes.
TLDR
When conservatively defined, DMX is prevalent in the natural history of bipolar II but uncommon in unipolar MDD, and the search for hypomanic features--ostensibly elation would not be one of those--during an index depressive episode could enhance the detection ofipolar II in otherwise pseudo-unipolar patients. Expand
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