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Path integration and the neural basis of the 'cognitive map'
TLDR
Theoretical studies suggest that the medial entorhinal cortex might perform some of the essential underlying computations by means of a unique, periodic synaptic matrix that could be self-organized in early development through a simple, symmetry-breaking operation. Expand
Coherent Theta Oscillations and Reorganization of Spike Timing in the Hippocampal- Prefrontal Network upon Learning
TLDR
H hippocampal/prefrontal coherence could lead to synchronization of reward predicting activity in prefrontal networks, tagging it for subsequent memory consolidation in rats learning new rules on a Y maze. Expand
Replay of rule-learning related neural patterns in the prefrontal cortex during sleep
TLDR
Recording neuron ensembles in the rat medial prefrontal cortex to study memory trace reactivation during SWS following learning and execution of cross-modal strategy shifts found that learning influenced which patterns were most strongly encoded and successively reactivated in the hippocampal/prefrontal network. Expand
Inhibition recruitment in prefrontal cortex during sleep spindles and gating of hippocampal inputs
TLDR
The results demonstrate that during sleep spindles, the cortex is functionnaly “deafferented” from its hippocampal inputs, based on processes of cortical origin, and presumably mediated by the strong recruitment of inhibitory interneurons. Expand
Hippocampal sharp wave bursts coincide with neocortical "up-state" transitions.
TLDR
Low-density neuronal ensemble recordings in rats reveal the interaction between synchronized activity in the hippocampus and neocortex, which highlights the interplay in the hippocampal/neocortical loop and may reflect joint memory trace reactivation inthe hippocampus and in the neocortex. Expand
Local Sensory Cues and Place Cell Directionality: Additional Evidence of Prospective Coding in the Hippocampus
TLDR
It is shown here, with data from three experiments, that multimodal, local sensory cues can change the directional properties of CA1 pyramidal cells, inducing bidirectionality in a significant proportion of place cells, hence decreasing the orthogonality of hippocampal output. Expand
Light sleep versus slow wave sleep in memory consolidation: a question of global versus local processes?
TLDR
This work draws on recent studies to suggest a link between light NREM and active potentiation, and between deep N REM and homeostatic regulation, and could serve as a key for interpreting the physiology of sleep stages and reconciling inconsistencies in terminology. Expand
Attractor neural networks storing multiple space representations: A model for hippocampal place fields
TLDR
A recurrent neural network model storing multiple spatial maps, or ``charts'', is analyzed, and results suggest a quantitative parallel between theories of hippocampal function in different animal species, such as primates and rodents. Expand
Oscillations in the prefrontal cortex: a gateway to memory and attention
TLDR
The profound modifications of the PFC neuronal network associated with changes in oscillatory coherence are controlled by neuromodulators such as dopamine, which thereby allow or prevent the formation of cell assemblies for information encoding and storage. Expand
The hippocampus: hub of brain network communication for memory
TLDR
This 'two-stage' model has been updated by new data from high-density electrophysiological recordings in animals that shed light on how information is encoded and exchanged between hippocampus, neocortex and subcortical structures such as the striatum. Expand
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