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PIK3CA mutations in human solid tumors: Role in sensitivity to various therapeutic approaches
Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases that regulate signaling pathways involved in cell proliferation, adhesion, survival and motility. The PI3K pathway is considered toExpand
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Mediterranean diet and cancer: epidemiological evidence and mechanism of selected aspects
BackgroundPopulations living in the area of the Mediterranean Sea suffered by decreased incidence of cancer compared with those living in the regions of northern Europe and US countries, attributedExpand
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Effects of tunnelling on pile foundations
Abstract An efficient analysis method is presented for estimating the effects induced by tunnelling on existing pile foundations. The method is based on a two-stage procedure: (1) an estimate of theExpand
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Mediterranean Diet and Cardiovascular Risk Factors: A Systematic Review
The aim of this paper was to systematically review and analyze the epidemiological evidence on the role of Mediterranean diet (MD) in the prevention of cardiovascular diseases (CVD). Fifty-eightExpand
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Factors Associated with Colorectal Cancer in the Context of the Mediterranean Diet: A Case-Control Study
Recent evidence demonstrates that increased adherence to the Mediterranean diet (MD) may prevent colorectal cancer (CRC). The aim of this study was to evaluate the association between health-relatedExpand
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Risk of Hepatocellular Carcinoma in Workers Exposed to Chemicals
Context Studies on experimental animals have shown liver is a common target of chemical carcinogens; this might suggest that occupational exposure to chemicals is another risk factor for HCC.Expand
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Health related quality of life in colorectal cancer patients: state of the art
BackgroundColorectal cancer (CRC) is the third most commonly diagnosed cancer in males and the second in females with a progressive increase in prevalence in industrialized countries. The loss ofExpand
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Markers of bile duct tumors.
Biliary tract carcinomas are relatively rare, representing less than 1% of cancers. However, their incidence has increased in Japan and in industrialized countries like the USA. Biliary tract tumorsExpand
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The technical feasibility of biomass gasification for hydrogen production
Biomass gasification for energy or hydrogen production is a field in continuous evolution, due to the fact that biomass is a renewable and CO2 neutral source. The ability to produce biomass-derivedExpand
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Specific Alterations of MicroRNA Transcriptome and Global Network Structure in Colorectal Carcinoma after Cetuximab Treatment
The relationship between therapeutic response and modifications of microRNA (miRNA) transcriptome in colorectal cancer (CRC) remains unknown. We investigated this issue by profiling the expression ofExpand
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