• Publications
  • Influence
Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat
Background Bone-marrow derived mesenchymal stem cells (MSCs) reduce the severity of evolving acute lung injury (ALI), but their ability to repair the injured lung is not clear. A study was undertakenExpand
  • 195
  • 11
  • PDF
ClockIt: collecting quantitative data on how beginning software developers really work
TLDR
The Information Technology sector is suffering from a dramatic reduction in the number of students studying the field and subsequently entering the IT market. Expand
  • 37
  • 7
Effects of Intratracheal Mesenchymal Stromal Cell Therapy during Recovery and Resolution after Ventilator-induced Lung Injury
Background:Mesenchymal stromal cells (MSCs) have been demonstrated to attenuate acute lung injury when delivered by intravenous or intratracheal routes. The authors aimed to determine the efficacy ofExpand
  • 83
  • 4
Immunogenicity of allogeneic mesenchymal stem cells
Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule‐1 (VCAM‐1).Expand
  • 142
  • 3
Gene-eluting stents: adenovirus-mediated delivery of eNOS to the blood vessel wall accelerates re-endothelialization and inhibits restenosis.
Drug-eluting stents for coronary artery disease results in inhibition of smooth muscle cell (SMC) and endothelial cells which may increase the risk of stent thrombosis. In this study, we attempted toExpand
  • 76
  • 3
Bone marrow-derived mesenchymal stem cells promote angiogenic processes in a time- and dose-dependent manner in vitro.
Bone marrow-derived mesenchymal stem cells (MSCs) have received much attention as a potential treatment for myocardial infarction because of their potential to integrate into the host myocardium andExpand
  • 132
  • 2
  • PDF
Response of mesenchymal stem cells to the biomechanical environment of the endothelium on a flexible tubular silicone substrate.
Understanding the response of mesenchymal stem cells (MSCs) to forces in the vasculature is very important in the field of cardiovascular intervention for a number of reasons. These include theExpand
  • 81
  • 2
Enhanced lipoplex‐mediated gene expression in mesenchymal stem cells using reiterated nuclear localization sequence peptides
Mesenchymal stem cells (MSC) are widely regarded as a promising tool for cellular therapy applications, and genetic modification by safe, liposome‐based vectors may enhance their therapeuticExpand
  • 37
  • 1
Radiation-Induced Alterations of Osteogenic and Chondrogenic Differentiation of Human Mesenchymal Stem Cells
While human mesenchymal stem cells (hMSCs), either in the bone marrow or in tumour microenvironment could be targeted by radiotherapy, their response is poorly understood. The oxic effects onExpand
  • 18
  • 1
  • PDF
Genetically modified mesenchymal stem cells and their clinical potential in acute cardiovascular disease.
Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential to differentiate into various tissues of mesodermal origin. They can be isolated from bone marrow andExpand
  • 23
  • 1
  • PDF