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Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
The Discriminant Analysis of Principal Components (DAPC) is introduced, a multivariate method designed to identify and describe clusters of genetically related individuals that performs generally better than STRUCTURE at characterizing population subdivision. Expand
The estimation of population differentiation with microsatellite markers
This review discusses the consequences of different temporal and spatial sampling strategies on differentiation estimation, and moves to statistical problems directly associated with the estimation of population structuring itself, with particular emphasis on the effects of high mutation rates and mutation patterns of microsatellite loci. Expand
Does heterozygosity estimate inbreeding in real populations?
If inbreeding is the dominant mechanism, then the simulations indicate that consanguineous mating would have to be vastly more common than is predicted for most realistic populations, and if heterosis provides the answer, there need to be many more polymorphisms with major fitness effects and higher levels of linkage disequilibrium than are generally assumed. Expand
Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings
Transmissibility is substantially higher than that of seasonal flu, and comparable with lower estimates of R0 obtained from previous influenza pandemics, by analyzing the outbreak in Mexico, early data on international spread, and viral genetic diversity, which makes an early assessment of transmissibility and severity. Expand
The population genetics of clonal and partially clonal diploids.
The consequences of variable rates of clonal reproduction on the population genetics of neutral markers are explored in diploid organisms within a subdivided population (island model). We use bothExpand
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. Expand
Geography predicts neutral genetic diversity of human populations
It is proposed that the ancestors of all modern humans originated in East Africa and that, around 100,000 years ago, some modern humans left the African continent and subsequently colonised the entire world, displacing previously established human species such as Neanderthals in Europe. Expand
Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity
The phylogenetic analysis suggests that Y. pestis evolved in or near China and spread through multiple radiations to Europe, South America, Africa and Southeast Asia, leading to country-specific lineages that can be traced by lineage-specific SNPs. Expand
Female-biased dispersal in the monogamous mammal Crocidura russula: evidence from field data and microsatellite patterns.
It is demonstrated that a state-biased dispersal can be directly inferred from microsatellite genotype distributions, which opens new perspectives for empirical studies in this area. Expand