Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
The Discriminant Analysis of Principal Components (DAPC) is introduced, a multivariate method designed to identify and describe clusters of genetically related individuals that performs generally better than STRUCTURE at characterizing population subdivision.
EASYPOP (version 1.7): a computer program for population genetics simulations.
- F. Balloux
- Computer ScienceJournal of Heredity
- 1 May 2001
The software EASYPOP is developed, an individual-based model that simulates neutral loci datasets under a very broad range of conditions and the possibility of testing new software devoted to population genetics analysis under nontrivial conditions.
The estimation of population differentiation with microsatellite markers
This review discusses the consequences of different temporal and spatial sampling strategies on differentiation estimation, and moves to statistical problems directly associated with the estimation of population structuring itself, with particular emphasis on the effects of high mutation rates and mutation patterns of microsatellite loci.
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.
Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings
Transmissibility is substantially higher than that of seasonal flu, and comparable with lower estimates of R0 obtained from previous influenza pandemics, by analyzing the outbreak in Mexico, early data on international spread, and viral genetic diversity, which makes an early assessment of transmissibility and severity.
Does heterozygosity estimate inbreeding in real populations?
If inbreeding is the dominant mechanism, then the simulations indicate that consanguineous mating would have to be vastly more common than is predicted for most realistic populations, and if heterosis provides the answer, there need to be many more polymorphisms with major fitness effects and higher levels of linkage disequilibrium than are generally assumed.
The population genetics of clonal and partially clonal diploids.
The consequences of variable rates of clonal reproduction on the population genetics of neutral markers are explored in diploid organisms within a subdivided population (island model). We use both…
Geography predicts neutral genetic diversity of human populations
Female-biased dispersal in the monogamous mammal Crocidura russula: evidence from field data and microsatellite patterns.
- L. Favre, F. Balloux, J. Goudet, N. Perrin
- Environmental ScienceProceedings of the Royal Society of London…
- 22 January 1997
It is demonstrated that a state-biased dispersal can be directly inferred from microsatellite genotype distributions, which opens new perspectives for empirical studies in this area.
An African origin for the intimate association between humans and Helicobacter pylori
It is established that anatomically modern humans were already infected by H. pylori before their migrations from Africa and demonstrate that H.pylori has remained intimately associated with their human host populations ever since.