F. Balkwill

Publications400
h-index100
Citations54,606
Highly Influential Citations1,565
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Cancer-related inflammation
TLDR
The molecular pathways of this cancer-related inflammation are now being unravelled, resulting in the identification of new target molecules that could lead to improved diagnosis and treatment.
View on Nature
Inflammation and cancer: back to Virchow?
View on Elsevier
Cancer and the chemokine network
  • F. Balkwill
  • Biology, Medicine
    Nature Reviews Cancer
  • 1 July 2004
TLDR
Insight is provided into host–tumour interactions, such as the role of the leukocyte infiltrate, and into the mechanisms that determine the metastatic potential and site-specific spread of cancer cells.
View on Springer
Tumour necrosis factor and cancer
  • F. Balkwill
  • Medicine, Biology
    Nature Reviews Cancer
  • 1 May 2009
Tumour necrosis factor (TNF) is a major inflammatory cytokine that was first identified for its ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to harness this…
View on Nature
Guidelines for the welfare and use of animals in cancer research
TLDR
New guidelines on the welfare and use of animals in cancer research are provided, including recommendations on all aspects of cancer research, including: study design, statistics and pilot studies; choice of tumour models and humane endpoints.
View on Nature
The tumor microenvironment at a glance
Cancers are not just masses of malignant cells but complex ‘rogue’ organs, to which many other cells are recruited and can be corrupted by the transformed cells. Interactions between malignant and…
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Smoldering and polarized inflammation in the initiation and promotion of malignant disease.
View on PubMed
Rethinking ovarian cancer: recommendations for improving outcomes
TLDR
Nine major recommendations that should be taken to improve the outcome for women with ovarian cancer are outlined in this Opinion article.
View on Nature
The significance of cancer cell expression of the chemokine receptor CXCR4.
  • F. Balkwill
  • Biology, Chemistry
    Seminars in cancer biology
  • 1 June 2004
View on PubMed
Paraneoplastic thrombocytosis in ovarian cancer.
TLDR
Findings support the existence of a paracrine circuit wherein increased production of thrombopoietic cytokines in tumor and host tissue leads to paraneoplasticThrombocytosis, which fuels tumor growth.
View on PubMed
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