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Bacteriophage T4 Genome
SUMMARY Phage T4 has provided countless contributions to the paradigms of genetics and biochemistry. Its complete genome sequence of 168,903 bp encodes about 300 gene products. T4 biology and itsExpand
Structural basis of Sec-independent membrane protein insertion by YidC
Newly synthesized membrane proteins must be accurately inserted into the membrane, folded and assembled for proper functioning. The protein YidC inserts its substrates into the membrane, therebyExpand
Silk Fibroin of Bombyx mori Is Secreted, Assembling a High Molecular Mass Elementary Unit Consisting of H-chain, L-chain, and P25, with a 6:6:1 Molar Ratio*
Silk fibroin produced by the silkwormBombyx mori consists of a heavy chain, a light chain, and a glycoprotein, P25. The heavy and light chains are linked by a disulfide bond, and P25 associates withExpand
Structure and morphogenesis of bacteriophage T4
Bacteriophage T4 is one of the most complex viruses. More than 40 different proteins form the mature virion, which consists of a protein shell encapsidating a 172-kbp double-stranded genomic DNA, aExpand
Balance between Distinct HP1 Family Proteins Controls Heterochromatin Assembly in Fission Yeast
ABSTRACT Heterochromatin protein 1 (HP1) is a conserved chromosomal protein with important roles in chromatin packaging and gene silencing. In fission yeast, two HP1 family proteins, Swi6 and Chp2,Expand
Morphogenesis of the T4 tail and tail fibers
Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electronExpand
Nuclear Transport of the Major Capsid Protein Is Essential for Adeno-Associated Virus Capsid Formation
ABSTRACT Adeno-associated virus capsids are composed of three proteins, VP1, VP2, and VP3. Although VP1 is necessary for viral infection, it is not essential for capsid formation. The other capsidExpand
Structure of the cell-puncturing device of bacteriophage T4
Bacteriophage T4 has a very efficient mechanism for infecting cells. The key component of this process is the baseplate, located at the end of the phage tail, which regulates the interaction of theExpand
Atg38 is required for autophagy-specific phosphatidylinositol 3-kinase complex integrity
Atg38 provides a physical linkage between the Vps15–Vps34 and Atg14–Vps30 subcomplexes to facilitate PI3-kinase complex I formation.
AAA+ Ring and Linker Swing Mechanism in the Dynein Motor
Summary Dynein ATPases power diverse microtubule-based motilities. Each dynein motor domain comprises a ring-like head containing six AAA+ modules and N- and C-terminal regions, together with a stalkExpand