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Prevention of venous thromboembolism.
TLDR
The risk factors for VTE among hospitalized patients are outlined, the efficacy and safety of alternative prophylaxis regimens are reviewed, and recommendations regarding the most suitable prophymic regimens based on the estimated risk are provided. Expand
Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
TLDR
A large proportion of hospitalised patients are at risk for VTE, but there is a low rate of appropriate prophylaxis, which reinforces the rationale for the use of hospital-wide strategies to assess patients' VTE risk and to implement measures that ensure that at-risk patients receive appropriate proPHylaxis. Expand
Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE)
TLDR
This risk prediction tool uses readily identifiable variables to provide robust prediction of the cumulative six month risk of death or myocardial infarction and can guide patient triage and management across the spectrum of patients with acute coronary syndrome. Expand
Venous thromboembolism (VTE) in Europe. The number of VTE events and associated morbidity and mortality.
TLDR
The estimated total number of symptomatic VTE events (range based on probabilistic sensitivity analysis) per annum within the six EU countries was 465,715; almost three-quarters of all VTE-related deaths were from hospital-acquired VTE. Expand
A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. The Worcester DVT Study.
TLDR
Extrapolation of the data from this population-based study suggests that there are approximately 170,000 new cases of clinically recognized venous thromboembolism in patients treated in short-stay hospitals in the United States each year, and 99,000 hospitalizations for recurrent disease. Expand
Decline in rates of death and heart failure in acute coronary syndromes, 1999-2006.
TLDR
Improvements in the management of patients with ACS were associated with significant reductions in the rates of new heart failure and mortality and in rates of stroke and mycoardial infarction at 6 months. Expand
Baseline characteristics, management practices, and in-hospital outcomes of patients hospitalized with acute coronary syndromes in the Global Registry of Acute Coronary Events (GRACE).
TLDR
The Global Registry of Acute Coronary Events (GRACE) describes the epidemiology, management, and outcomes of patients with ACS and provides a detailed and comprehensive global description of the spectrum of Patients with ACS. Expand
Estimated annual numbers of US acute‐care hospital patients at risk for venous thromboembolism
TLDR
Estimation of the number of US acute‐care hospital inpatients who were at risk for VTE according to criteria established by the Seventh American College of Chest Physicians (ACCP) Consensus Conference on Antithrombotic and Thrombolytic Therapy guidelines for V TE prevention found 7,742,419 met ACCP VTE risk criteria. Expand
Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE)
TLDR
A risk-averse strategy to angiography appears to be widely adopted and systematic and accurate risk stratification may allow higher-risk patients to be selected for revascularisation procedures, in contrast to current international practice. Expand
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