fMRI activation during spike and wave discharges in idiopathic generalized epilepsy.
- Y. Aghakhani, A. Bagshaw, J. Gotman
- Biology, MedicineBrain : a journal of neurology
- 1 May 2004
The presence of a thalamic BOLD response in most patients provided, for the first time in a group of human patients, confirmation of the evidence ofThalamic involvement seen in animal models, and brings a new light to the pathophysiolocal mechanisms generating GSW.
Intrinsic epileptogenicity of human dysplastic cortex as suggested by corticography and surgical results
- A. Palmini, A. Gambardella, Hyoung-Ihl Kim
- MedicineAnnals of Neurology
- 1 April 1995
It is concluded that CDyLs are highly and intrinsically epilepsyptogenic, and that intraoperative ECoG identification of this intrinsically epileptogenic dysplastic cortical tissue is crucial to decide the extent of excision for best seizure control.
The role of the limbic system in experiential phenomena of temporal lobe epilepsy
- P. Gloor, A. Olivier, L. Quesney, F. Andermann, S. Horowitz
- Psychology, MedicineAnnals of Neurology
- 1 August 1982
Patients with medically intractable temporal lobe epilepsy who were investigated with chronic, stereotaxically implanted intracerebral electrodes reported perceptual experiential phenomena that mainly consisted of perceptual hallucinations or illusions, memory flashbacks, illusions of familiarity, forced thinking, or emotions.
Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging
- C. Watson, F. Andermann, G. Leroux
- Biology, PsychologyNeurology
- 1 September 1992
A protocol to measure the volumes of the amygdala and as much of the hippocampus using high-resolution MRI to clarify the role of this structure in the pathogenesis of temporal lobe epilepsy is developed.
Hypothalamic hamartomas and ictal laughter: Evolution of a characteristic epileptic syndrome and diagnostic value of magnetic resonance imaging
- S. Berkovic, F. Andermann, D. Melanson, R. Ethier, W. Feindel, P. Gloor
- Psychology, MedicineAnnals of Neurology
- 1 May 1988
The epileptic syndrome associated with hypothalamic hamartomas characteristically begins in infancy with laughing seizures and between the ages of 4 and 10 years, the clinical and electroencephalographic features of secondary generalized epilepsy develop.
The spectrum of SCN1A-related infantile epileptic encephalopathies.
- L. Harkin, J. Mcmahon, I. Scheffer
- Medicine, PsychologyBrain : a journal of neurology
- 1 March 2007
Knowing of an expanded spectrum of epileptic encephalopathies associated with SCN1A mutations allows earlier diagnostic confirmation for children with these devastating disorders, including cryptogenic generalized epilepsy and cryptogenic focal epilepsy.
Complex visual hallucinations. Clinical and neurobiological insights.
- M. Manford, F. Andermann
- Psychology, MedicineBrain : a journal of neurology
- 1 October 1998
It is suggested that perturbation of a distributed matrix may explain the production of similar, complex mental phenomena by relatively blunt insults at disparate sites.
MRI volumetric measurement of amygdala and hippocampus in temporal lobe epilepsy
- F. Cendes, F. Andermann, G. Leroux
- Medicine, PsychologyNeurology
- 1 April 1993
MRI volumetric measurements of the amygdala, the hippocampal formation, and the anterior temporal lobe in a group of 30 patients with intractable temporal lobe epilepsy and in seven patients with extratemporal lobe foci showed lateralization of measurable atrophy consistent with that derived from extracranial and intracranial EEG examinations.
Mutations in the X-linked filamin 1 gene cause periventricular nodular heterotopia in males as well as in females.
The results demonstrate the sensitivity and specificity of DNA testing for FLN1 mutations and have important functional implications for models ofFLN1 protein function in neuronal migration.
Congenital malformations due to antiepileptic drugs
- S. Kaneko, D. Battino, T. Teranishi
- MedicineEpilepsy Research
- 1 February 1999
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