Exploration of the Effects of High Hydrostatic Pressure on Microbial Growth, Physiology and Survival: Perspectives from Piezophysiology
- F. Abe
- BiologyBioscience, biotechnology and biochemistry
- 23 October 2007
The challenges in piezophysiology are to discover whether the physiological responses of living cells to high pressure are relevant to their growth and to identify the critical factors in cell viability and lethality under high pressure from the general and organism-specific viewpoints.
Pressure-regulated metabolism in microorganisms.
- F. Abe, C. Kato, K. Horikoshi
- BiologyTrends in Microbiology
- 1 July 2000
The biotechnological potential of piezophiles.
- F. Abe, K. Horikoshi
- BiologyTrends in Biotechnology
- 1 March 2001
Tryptophan Permease Gene TAT2 Confers High-Pressure Growth in Saccharomyces cerevisiae
- F. Abe, K. Horikoshi
- BiologyMolecular and Cellular Biology
- 1 November 2000
High-pressure sensing in yeast in comparison with the TOR-signaling pathway is described and an important factor involved in adaptation of organisms to high-pressure environments is discussed.
Pressure-Induced Differential Regulation of the Two Tryptophan Permeases Tat1 and Tat2 by Ubiquitin Ligase Rsp5 and Its Binding Proteins, Bul1 and Bul2
Evidence is presented that the two tryptophan permeases Tat1 and Tat2 are differentially regulated by Rsp5 ubiquitin ligase in response to high hydrostatic pressure and that hydrostaticpressure is a unique tool for elucidating the dynamics of integral membrane protein functions as well as for probing lipid microenvironments where they localize.
Control of protein and sterol trafficking by antagonistic activities of a type IV P-type ATPase and oxysterol binding protein homologue.
- Baby-Periyanayaki Muthusamy, S. Raychaudhuri, T. Graham
- Biology, ChemistryMolecular Biology of the Cell
- 15 June 2009
A homeostatic feedback mechanism in which appropriately regulated flippase activity in the Golgi complex helps establish a plasma membrane phospholipid organization that resists sterol extraction by a sterol binding protein.
Global Screening of Genes Essential for Growth in High-Pressure and Cold Environments: Searching for Basic Adaptive Strategies Using a Yeast Deletion Library
- F. Abe, H. Minegishi
- BiologyGenetics
- 1 February 2008
A novel route to gaining insights into cellular functions and the genetic network from growth properties of deletion mutants under high pressure and low temperature is offered.
Bap31 Enhances the Endoplasmic Reticulum Export and Quality Control of Human Class I MHC Molecules1
- J. J. Ladasky, Sarah Boyle, M. Edidin
- BiologyJournal of Immunology
- 1 November 2006
It is proposed that Bap31 performs quality control on class I molecules in two distinct phases: first, by exporting peptide-loaded class I molecule to the ER/Golgi intermediate compartment, and second, by retrievingclass I molecules that have lost peptides in the acidic post-ER environment.
Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology.
- X. Guan, C. M. Souza, H. Riezman
- Biology, ChemistryMolecular Biology of the Cell
- 1 April 2009
Using lipid analysis by mass spectrometry and a genetic approach on mutants in sterol metabolism, it is shown that cells adjust their membrane composition in response to mutant sterol structures preferentially by changing their sphingolipid composition.
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