F. le Caer

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Steroid binding to human lymphocytes was previously detected by a fluorescence assay (Tubiana et al., 1984). In the present study fluorescence assays were carried out with a macromolecular complex constituted by covalently binding steroid to bovine serum albumin (BSA). In this way it was possible to eliminate transmembrane diffusion and confine the study to(More)
OBJECTIVES Our main aim was to describe and explore a multidisciplinary approach to the management of elderly patients with cancer, who constitute a heterogeneous population. MATERIALS AND METHODS This descriptive study was performed between October 2009 and September 2010. Patients with cancer ≥ 70 years of age were included. Some underwent a simplified(More)
The role played by T lymphocytes in myelopoiesis has been established in in vitro studies. Dysregulation of the lymphoid system results in quantitative and, more rarely, qualitative abnormalities of myelopoiesis. The authors report the clinical data of two cases of peripheral T cell lymphoma associated with an AREB type of dysmyelopoiesis. The fact that(More)
Ontogeny and development of phenotypically defined T-cell subsets in humans, are the source of controversy. Cord blood represents a relevant model for the study of the normal T-cell differentiation pathway. We identified T lymphocytes subsets with monoclonal antibodies (Mab) in human cord blood and adults controls in an indirect immunofluorescence assay and(More)
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