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The aim of the study was to investigate and compare the clinical manifestations between HLA-B27(+) and HLA-B27(-) ankylosing spondylitis (AS) patients in order to obtain knowledge of the impact of HLA-B27 status on AS, and to inform clinical treatment. A nationwide epidemiological investigation was performed from November 2008 to October 2010. The(More)
nicotinic acetylcholine receptor with ligands: the roles of Gln117 and other residues of the receptor in agonist binding " , An efficient implementation for determining volume polarization in self-consistent reaction field theory " , Combined 3D-QSAR modeling and molecular docking study on indolinone derivatives as inhibitors of 3-Phosphoinositide-dependent(More)
Fundamental reaction mechanism and free energy profile for (-)-cocaine hydrolysis catalyzed by cocaine esterase " , J. molecular conformations of indolizidine (-)-235B' in solution " , Theo. Computational simulations of the interactions between acetyl-coenzyme-A carboxylase and clodinafop: Resistance mechanism due to active and nonactive site mutations " ,(More)
Ischemic stroke (IS) is a multifactorial disorder, and genetic factors act as important contributors to its onset and progression. Inflammation is a key event that is closely associated with the pathophysiology of IS. The association of genetic polymorphisms of inflammatory cytokines with IS remains poorly understood. We investigated the relationship(More)
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