F X Hasselberger

Learn More
Four methods are described for the preparation of enzymically active, water-insoluble derivatives of the antineoplastic enzyme asparaginase from Escherichia coli B. All methods lead to covalent bond formation, and three of the derivatives are more stable at 37° than free enzyme in solution. Derivatives prepared by the Woodward's reagent method are slightly(More)
  • 1