F W Flickinger

Learn More
Echocardiography (ECHO) is useful to document changes in left ventricular mass (LVM) in groups of patients, but may be too variable for use in the individual patient. Magnetic resonance imaging (MRI) may be a more precise and reliable method to quantify the mass of the left ventricule. This study reports the accuracy, precision, and reliability of LVM(More)
We investigated the utility of bone marrow MRI for diagnosing marrow metastases from breast cancer compared with radionuclide bone scan, iliac crest marrow biopsy with histology and antibody immunostaining, and clinical follow-up. We report the results of 43 MRI studies in 32 patients and discuss the evolution and comparison of optimal MRI techniques. MRI(More)
Using gadolinium-DTPA enhanced MRI we analyzed the enhancement characteristics of palpable breast masses in 23 patients--10 cancers and 13 benign lesions. The most specific finding for separating benign from malignant lesions was a ratio of maximum intensity change divided by the time interval during which this first occurred. Designated ranges of this(More)
Giant vascular neoplasms in neonates generally require aggressive medical or surgical therapy for treatment of complications. Steroids, chemotherapy, embolization, radiation, and surgery have all been used with short-term beneficial and sometimes unknown long-term side effects. A new modality of treatment, alpha-interferon, has recently been described. The(More)
Left ventricular mass (LVM) is an important consideration in the management of cardiac hypertrophy associated with hypertrophic cardiomyopathy (HCM), systemic hypertension, and other diseases. A brief MRI cardiac imaging procedure used to monitor regression of LVM during treatment would be beneficial in management of these patients, since echocardiograms(More)
The magnetic resonance (MR) findings are presented of a nonfunctioning mediastinal paraganglioma on both T1- and T2-weighted magnetic resonance images. The MR characteristics of this tumor differentiate it from previously reported functioning mediastinal paragangliomas (pheochromocytoma) and from other benign mediastinal neoplasms, although mediastinal(More)
The thoracic spinal cords of five mongrel dogs were imaged with a 1.5 T MR scanner before and after trauma induced by a well-established method of spinal cord impaction that produces central cord hemorrhagic necrosis. The anesthetized dogs were studied acutely with a 5-in. circular surface coil, 12-cm field of view, sagittal and axial partial-saturation (TR(More)
Fourteen patients (16 sites) with clinical and/or radiographic evidence of neuropathic osteoarthropathy (Charcot joints) were evaluated with combined indium-111-leukocyte (111In-WBC) and technetium-99m-methylene diphosphonate (99mTc-MDP) bone imaging for suspected osteomyelitis. Magnetic resonance (MR) images were obtained in seven patients. Using a(More)
Chordomas are uncommon primary skeletal neoplasms arising from notochordal remnants. Approximately 50% arise in the sacrum, 35% in the clivus, and less than 15% in the true vertebrae. We report magnetic resonance (MR) studies of four unusual primary chordomas, three in the lumbar region (L1, L2, and L3) and one in the Meckel cave. It is often difficult to(More)