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A G309D mutation in the PINK1 gene in a consanguineous Spanish kindred with seven siblings, three of whom are clinically affected, has recently been shown to be a cause of the PARK6 form of autosomal-recessive Parkinson's syndrome. In this family, we studied pre- and postsynaptic dopaminergic function using 123I-FP-CIT- and 123I-iodobenzamide-SPECT to(More)
Depression is a common symptom in Parkinson's disease (PD) and it is present in up to 40% of the patients. The cause of depression in PD is thought to be related to disturbance of monoamine neurotransmission. The endogenous cannabinoid system mediates different brain processes that play a role in the control of behaviour and emotions. Cannabinoid function(More)
Lymphedema of the penis and scrotum is a rare entity characterized by enlargement of the skin and subcutaneous tissue of the genital region due to lymphatic drainage impairment. This clinical condition is more frequent in tropical countries due to a higher incidence of filariasis, which, in turn, is the main etiology. We describe the case of a 33-year-old(More)
A systematic study of the population probabilities of microsecond isomers produced following the fragmentation of 208 Pb projectiles at 1 GeV/nucleon has been undertaken at the SIS/FRS facility at GSI Darmstadt. Gamma decays from approximately 20 isomeric states, mainly in the rare-earth and transitional nuclei with Aϳ180, were identified and the(More)
Lagging models of heat conduction, such as the Dual-Phase-Lag or the Single-Phase-Lag models, lead to heat conduction equations in the form of partial differential equations with delays or to partial differential equations of hyperbolic type, and have been considered to model microscale heat transfer in engineering problems or bio-heat transfer in medical(More)
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