F. V. de Sales

Learn More
BACKGROUND Clinical outcome of patients with high-risk melanoma cannot be reliably predicted on the basis of classical histopathological examination. Our study aimed to determine in melanoma metastases a gene expression profile associated with patient survival, and to identify and validate marker(s) of poor clinical outcome. METHODS Skin and lymph node(More)
Virtual Histology (VH) is a new medical imaging technique that allows the assessment of atherosclerotic plaque composition, a potential useful tool for the evaluation of individuals with coronary disease. Empirical observation has suggested that plaque areas adjacent to dense calcium (DC) are frequently coded as necrotic core (NC) in VH images. The main(More)
BACKGROUND Clinical outcome of high-risk melanoma patients is not reliably predicted from histopathological analyses of primary tumours and is often adjusted during disease progression. Our study aimed at extending our previous findings in skin metastases to evaluate the prognostic value of tyrosinase-related protein 1 (TYRP1) in lymph node metastases of(More)
In-vivo atherosclerotic plaque composition has been currently assessed by means of techniques based on spectral analysis of backscattered intravascular ultrasonic signals. Conversely, conventional IVUS images are based only on amplitude envelope of ultrasonic signals, discarding some frequency information and, consequently, disabling tissue characterization(More)
BACKGROUND We previously demonstrated an inverse correlation between tyrosinase-related protein 1 (TYRP1) mRNA expression in melanoma metastases and patient survival. However, TYRP1 protein was not detected in half of tissues expressing mRNA and did not correlate with survival. Based on a study reporting that 3' untranslated region (UTR) of TYRP1 mRNA(More)
This paper analyses a strategy for ischemia detection based on wavelet decomposition of the ST segment. The wavelet transform is used as a pre-processing tool for linear discriminant classifier. In order to minimize generalization problems caused by correlations between the classification variables, a selection algorithm is employed to choose a subset of(More)
We report the results of time-integrated and time-resolved photoluminescence spectroscopy on red-emitting self-organized InAs/Al 0.6 Ga 0.4 As quantum dots with indirect barriers. Spatially resolved PL measurements confirm that carriers excited in the Al 0.6 Ga 0.4 As barriers are consistent with a carrier hopping process between dots, a result also(More)
We have investigated the quantum dot (QD) carrier capture mechanism using continuous wave photoluminescence as a function of the optical excitation intensity using a sample with a QD density gradient across its surface ranging from 0 to 1.8 £ 10 11 cm 22. Modelling of the carrier kinetics has been described by a set of three coupled rate equations(More)
This article reviews Malformations of Cortical Development (MCD) diagnosed by Magnetic Resonance Imaging (MRI) in a series of patients with epilepsy. This study spans a five year period. The frequency of these malformations was 7.1%. Most of these were focal or multifocal and the most common ones were polymicrogyria (35.3% of the patients), heterotopia(More)
  • 1