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Gaseous butadiene (BUT) was mutagenic towards S. typhimurium strain TA 1530 when the incubation mixture was supplemented with a NADPH-fortified rat liver microsomal preparation; mutagenicity increased with the dose. A significant mutagenic effect was similarly observed when the petri dishes, containing the bacteria but no metabolic activation system, were(More)
The present study carries out output-only modal analysis using two blind source separation (BSS) techniques, namely independent component analysis and second-order blind identification. The concept of virtual source is exploited and renders the application of these BSS techniques possible. The proposed modal analysis method is illustrated using numerical(More)
The mutagenic activity of styrene was investigated by incubating the strains of Salmonella typhimurium in gaseous atmospheres. The sensitive strains were TA1530, TA1535 and TA100. In that method, styrene regularly showed a mutagenic activity in the presence of a fortified liver post-mitochondrial fraction. The mutagenic activity remained weak. Moreover, it(More)
1. Abstract Structural design must often reconcile some conflicting goals and must integrate multiple and various constraints. It can become a real challenging task which asks great know-how and very good intuition. Topological optimization tools may help engineers to solve complicated design problems and to find new ideas or innovating design concepts.(More)
The mutagenicity of N-nitrosodiethanolamine and its mono- and di-acetyl derivatives was tested in the S. typhimurium test system, in cytogenetic studies and in the micronucleus test. N-nitrosodiethanolamine had no mutagenic effects towards several strains of S. typhimurium either in the absence or in the presence of metabolic activating systems. Its(More)