F. P. Sidel'kovskaya

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Compounds were discovered among ~,m-bispiperidinoalkanes with pronounced radioprotective activity [i]. It was of interest to look for new radioprotectors containing an aminoalkane group as the pharmacophore, and a pyrrolidone residue as a carrier, and also residues of natural fatty acids, which change the hydrophobic-hydrophilic balance in the direction of(More)
The presence of a pyrrolidone ring in the structure of organic compounds usually is associated with an increase in the hydrophilicity and ability for complex formation and a decrease in toxicity, and it favors some other properties useful for pharmacologically active substances [1]. This circumstance had an important role in the synthesis of some drugs(More)
EXPERIMENTAL (BIOLOGY) The antiviral activity of the test compounds was determined in tissue culture against variola vaccine virus (VVV), herpes simplex virus (HSV), classical avian plague virus (CAPV), Newcastel disease virus (NDV), vesicular stomatitis virus (VSV), Venezuelan equine encephalomyelitis virus (VEEN), and ECHO-6, using screening tests and(More)
Synthetic and natural macromolecular compounds are widely used in medicine [1, 2]. An important position among these belongs to poly(vinyl pyrrolidone) (PVP) [1 – 4] also known in pharmacy as polyvidone [2]. This polymer offers a unique combination of properties, including hydrophilicity, very low toxicity, and ability to form various complexes, in(More)
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