F. P. Fischer

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A family of supervised, nonparametric decision rules, based On tolerance regions, is described which includes the k-Nearest Neighbor decision rules when there are two classes. There are two practical reasons for doing so: first, a family of decision rules similar to the k-Nearest Neighbor rules can be specified which applies to a broader collection of(More)
Uraemic pruritus is a frequent and disabling symptom in patients on dialysis. The pathogenesis of uraemic pruritus is nevertheless still obscure. We investigated whether di(2-ethylhexyl)phthalate (DEHP), the most commonly used plasticizer in polyvinylchloride (PVC) haemodialysis tubings, is a possible pathogenetic factor in uraemic pruritus. Serum(More)
OBJECTIVES To evaluate the influence of the plasticizer metabolites of di(2-ethylhexyl)phthalate (DEHP), mono(2-ethylhexyl)phthalate (MEHP), 2-ethylhexanol (2-EH), and phthalic acid (PA) on various immune functions of polymorphonuclear blood leukocytes (PMNL) and monocytes (MN). MEHP, 2-EH, and PA are the main hydrolysis products of DEHP. Since DEHP is(More)
Excess morbidity and mortality among long-term hemodialysis patients because of infectious complications is partly caused by an impairment of cellular immune defense. We hypothesized this impairment is related to an abnormal carnitine metabolism also present in these patients. In a double-blind, randomized, placebo-controlled trial, we investigated the(More)
  • Adomavičius A Kaunas, Un, +72 authors Zemulis G
  • 2005
This study, supported by the European Communities, was carried out within the framework of the European Fusion Development Agreement. The views and opinions expressed herein do not necessarily reflect those of the European Commission. a series of studies within the European fusion programme, summarised in References 1 and 2, examined the safety,(More)