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OBJECTIVE The aim of this study was to assess the role of perivascular sensory nerves in modulating constrictions of intestinal submucosal arterioles. METHODS Arteriole constrictions were induced either by nerve released adenosine 5'-triphosphate (ATP) or exogenous ATP or phenylephrine (PE). Individual nerve shocks were used to elicit excitatory junction(More)
The present study was designed to evaluate the role of the endothelium as an effector organ of neurally mediated inhibition of vascular tone. Acetylcholine (ACh), either released by stimulation of the submucosal ganglia or applied exogenously, inhibited phenylephrine (PE)-induced constrictions in arterioles of the guinea pig intestinal submucosa.(More)
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