F. Marcelo

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PAPER α-N-Linked glycopeptides: conformational analysis and bioactivity as lectin ligands † ‡ § Natural N glycosylation involves a β anomeric linkage connecting the sugar to one asparagine residue of the protein. We herein report NMR and modelling based data on glycomimetics containing α glycosidic linkages. The bioactivity of α Gal containing glycopeptides(More)
Diseases that result from infection are, in general, a consequence of specific interactions between a pathogenic organism and the cells. The study of host-pathogen interactions has provided insights for the design of drugs with therapeutic properties. One area that has proved to be promising for such studies is the constituted by carbohydrates which(More)
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