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The laminar distribution of flash evoked field potential (VEP) was investigated in the visual cortical areas 17 and 18 b in freely moving rats. Averaged VEPs were recorded during stable relaxed wakefulness characterized behaviorally and polygraphically. The depth profiles of the main VEP components displayed polarity reversals in lamina V in every electrode(More)
22 rats of the Long-Evans strain (11 males and 11 females) were treated from the first to the eleventh postnatal day (pd) with daily subcutaneous injections of 4 mg/g body weight monosodium-L-glutamate (MSG) in aqua dest. Further 11 males and 7 females were used as controls and received isotonic NaCl-solution on the same days. The neurological investigation(More)
Active avoidance learning, retention and relearning were investigated before and after lesions of the interpeduncular nucleus (IP) of rat in a Y-maze and a jump test box. Preoperatively learnt active avoidance was abolished after the lesions and rats were not able to relearn it. Unconditioned escape responses remained unchanged in the Y-maze. Postoperative(More)
Simple reaction times (RT) to clicks, flashes and numerical signals were measured in four groups of subjects: 21 patients with mild presenile onset dementia of the Alzheimer type (PDAT, mean age 56 years), 14 patients with chronic cardiovascular disease and incipient cognitive deficit (mean age 55 years), 15 healthy older controls (mean age 53 years) and 16(More)
The postnatal development of open field (OF) behaviour of two groups of each 8 male hooded rats (Long-Evans strain) was compared after bilateral eye bulb removal on the seventh postnatal day (pd) in one group and sham-operation on the same day in the other group. Ambulatory activity of the deprived group was much increased (p less than 0.01) in all sessions(More)
Acoustically evoked potentials (AEP) were recorded and analysed in the basal forebrain (bf, nucleus basalis magnocellularis) and in the mesencephalic parabrachial nucleus cuneiformis (Cnf) of freely moving rats and the modulatory effects of electrical single stimulations within both cholinergic regions on these AEP are described. Bipolar electrodes were(More)
Different modulatory influences on visually evoked potentials (VEPs) of freely moving rats from two different cholinergic brain regions, the basal forebrain (bf, nucleus basalis magnocellularis) and the mesencephalic parabrachial nucleus cuneiformis (Cnf) are described. Bipolar stimulating electrodes were implanted in both regions and recording electrodes(More)